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Bio

デジタル研究開発

QSAR モデリングによる TBK1 阻害への道筋を定義する

TBK1 (TANK-binding kinase) が多くの疾患の病態生理学において重要な役割を果たしているにもかかわらず、なぜ FDA 承認された TBK1 阻害剤が市場に出ていないのでしょうか。
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材料

Co-occurrence analysis spots nanotechnology breakthroughs

Nanofibers, nanoplastics, and more are gaining research interest. See more nanotechnology breakthroughs through the lens of a CAS TrendScape analysis.
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新興の科学分野

Rare diseases: Impact, landscape, and possibilities

Rare diseases are difficult to treat, diagnose, and identify. As such, researchers are spending more effort in better understanding and treating these illnesses.
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デジタル研究開発

Identifying emerging trends in nanotechnology research

Combining advanced technologies with human curation identifies emerging trends in nanotechnology research.
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持続可能性

Innovating the chemical recycling of plastics

Recycling plastics can be challenging with traditional methods, leading to developments in chemical plastic recycling technology.
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材料

Idea in brief: Emerging trends and future opportunities for carbon nanotubes

Biomedicine, batteries, and more could be revolutionized by carbon nanotubes. See the full range of their applications.
|エグゼクティブサマリー
材料

CAS and Westlake University publication on biomaterials: Full-length report

This detailed technical report, published in collaboration with Westlake University, discusses the biomaterials landscape and how this field is rapidly changing.
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消費財

Evolving beauty: The rise of sustainable and natural ingredients for cosmetics

Learn about the shift towards sustainable and natural ingredients in cosmetics, supported by data from the CAS Content Collection™.
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創薬

Types of antisense oligonucleotides: Advancing therapeutic frontiers

Different types of antisense oligonucleotide therapies, such as exosomes and nanoparticles, offering new hope in genetic medicine.
|記事
材料

How nanotechnology delivers massive change in energy, biomedicine and more.

Unlock the potential of nanotechnology. Explore breakthroughs and challenges in energy, biomedicine, and more in our executive summary.
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材料

The material difference: How biomaterials are reshaping medicine and patient outcomes

This biomaterials Insights Report explores eight key areas transforming healthcare with self-healing implants, targeted drug delivery, and more.
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消費財

Unraveling the science behind artificial sweeteners

Uncover the science behind sweeteners, their health impacts, R&D trends, and investment data.
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材料

From batteries to drug delivery: Emerging applications of carbon nanotubes

Carbon nanotubes (CNTs) hold immense promise for batteries, composites, sensors, and more. Discover emerging trends on overcoming challenges and cutting edge applications.
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新興の科学分野

16 billion reasons for hope: How biomarkers are reshaping cancer outcomes

Biomarkers could help doctors catch cancer earlier, cure it more frequently, and perform treatments with fewer risks.
|エグゼクティブサマリー
持続可能性

Science fact vs. fiction: Can we recycle semiconductors?

Recycling semiconductors was once a far-off dream. However, new research and technology shows that this could become reality.
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知的財産

IP trends and opportunities: RNA therapeutics

See key insights on emerging RNA IP trends and possibilities for future innovations in this executive summary.
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新興の科学分野

Idea in brief: battling antibiotic resistant infections

As antimicrobial resistance becomes a larger problem, new approaches to battling infections are emerging.
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知的財産

Keeping a finger on the pulse of exosome IP and innovation

The landscape of exosomes has become highly competitive. See all the recent investments, innovations, and commercial opportunities.
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デジタル研究開発

Embracing the future of AI in the food industry

Discover how AI in the food industry is transforming production, innovation, and sustainability. Learn how AI can help you create smarter and more efficient food solutions.
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創薬

R&D Insight: Unique views into immuno-oncology

Immunotherapy is advancing with new approaches like CAR-T cell therapy, antibody-drug conjugates, and even checkpoint inhibitors.
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新興の科学分野

Scientific breakthroughs: 2024 emerging trends to watch

Stay ahead of the latest scientific breakthroughs that are accelerating the landscape of innovation and will transform global science in 2024
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創薬

Dealing with the challenges of drug discovery

The pharma industry is tackling major drug discovery challenges in several new ways. Have they been successful?
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持続可能性

Four uses for renewable feedstock in sustainable coatings

With the push towards increased sustainability, here are four ways coatings manufacturers are making use of renewable feedstock for their own products.
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創薬

R&D insights: The covalent inhibitor revolution

Covalent inhibitors were once avoided due to negative side effects, but new drugs have changed the landscape.
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バイオテクノロジー

The rise of covalent inhibitors in strategic therapeutic design

Drugs created with covalent inhibitors are becoming more popular than other types, owing to their unique mechanism of action.
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創薬

R&D insights ‐ 抗体薬物複合体

More than 100 antibody-drug conjugates are in clinical trials. These therapeutics combine the targeting abilities of antibodies with the power of chemotherapy to change cancer treatment.
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知的財産

Prior art search and analysis for scientific IP strategies

Incomplete prior art searches and analyses can lead to costly mistakes, leaving innovations and the value of intellectual property open to huge risk.
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新興の科学分野

Quantum dots win the 2023 Nobel Prize for Chemistry

CAS scientists discuss overlooked ideas that have yet to win a Nobel Prize. From OLEDs and MOFs to mRNA therapeutics and more, these ideas have reshaped science and technology.
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知的財産

Navigating patentability assessments in scientific industries

Patentability assessments in scientific industries come with significant challenges due to their complexity. However, CAS has tools designed to address these issues.
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新興の科学分野

CAS Symposium Explores Convergence of Biology and Chemistry in Emerging Therapeutics

CAS, the LaJolla Institute for Immunology, and Avidity Biosciences explore the convergence of biology and chemistry in emerging therapeutics for cancer, vaccines, and more.
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持続可能性

Going green with plant-based meat sustainability

With consumers changing their diets for personal and health reasons, innovation to increase quality and variety creates a diverse and competitive market.
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消費財

Multifunctional cosmetics: Developing a product that ‘does it all’

Hero ingredients can help create more advanced and versatile formulations than ever before as consumers slim down their cosmetic routines.
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新興の科学分野

Mars is calling, but how will Artemis fuel the journey?

Chemistry is powering space exploration with rocket fuel and engine technologies. Discover the advantages and challenges of using LOX/LH2 as a propellant for the Artemis mission.
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持続可能性

R&D insights: Sustainable catalysts for the future

Catalysts have been enabling green chemistry with applications in many industries.
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バイオテクノロジー

ウイルスとの戦いから腫瘍との戦いへ - mRNAワクチンをがん治療に活用する

COVID-19との闘いに革命をもたらしたmRNAワクチンのおかげで、私たちは免疫系の力を利用してがんを治療することができる。
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新興の科学分野

Top 10 emerging trends in biomaterials

Biomaterials like hydrogels, lipid nanoparticles, and exosomes are reshaping the landscape of drug delivery, diagnosis, and therapeutics.
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知的財産

Patent searching: Going beyond the basics to increase efficiency

Learn how leveraging patent tools and strategies can accelerate your path toward comprehensive searches and stronger insights.
|記事
新興の科学分野

Executive summary: What’s next in anti-aging treatments?

Research in anti-aging treatments has reached a pivotal point. How do new treatments, drugs, and clinical trials compare to time-tested practices?
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知的財産

The why’s and how’s of partnerships in scientific patent searching

Accelerate and improve the ROI of your IP and R&D initiatives by partnering with an industry and IP expert.
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持続可能性

Infographic: What can be done about microplastics?

Microplastics have infiltrated our entire world, even down to the water we drink and food we eat. Researchers are looking at new ways to address them.
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知的財産

Maximize opportunities with a patent landscape analysis

A successful patent landscape analysis can maximize opportunities and de-risk your company's R&D program and other initiatives.
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創薬

標的タンパク質分解誘導薬:​ 創薬における分子糊の展望

Induced-proximity target protein degradation (TPD) is a ground-breaking strategy in drug discovery that has emerged recently.
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持続可能性

スーパーキャパシタ技術 : グラフェンは遂にその潜在能力を発揮するのでしょうか

新しいスーパーキャパシタ技術は、電池の安全性の向上、充電時間の短縮、長寿命化につながる可能性がある。
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デジタル研究開発

Unlocking the power of dark data in chemistry R&D: Strategies for success

What is dark data, and how can it be used to unlock data insights and accelerate innovation for R&D?
|記事
新興の科学分野

Top emerging trends in mRNA therapeutics

mRNA vaccines created for COVID-19 have led to a slew of new research in mRNA therapeutics.
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バイオテクノロジー

Infographic: 3D printing is reshaping the future of biomedicine

Discover how advances in 3D printing materials and approaches have reshaped tissues and organ sourcing, drug delivery methods, and wound care.
|インフォグラフィック
バイオテクノロジー

Infographic: Top investment trends for RNA and the outlook ahead

Investment in RNA has grown beyond vaccines. Cancer, infectious diseases, and even liver diseases have all been identified for RNA medicines.
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持続可能性

Five ways to achieve sustainable medical packaging

Learn five ways to reduce waste and use biodegradable materials to develop sustainable sterile packaging options for medical devices.
|記事
新興の科学分野

What you need to know about PEG immunogenicity

PEG immunogenicity is a challenge that affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery.
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新興の科学分野

Peer reviewed publication: New discoveries on emerging microbiome trends

This publication in the ACS Chemical Neuroscience Journal details a landscape analysis of emerging trends in the gut microbiome space.
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新興の科学分野

Recognizing the potential of the gut microbiome

Created in collaboration with Bayer AG, this report discusses the latest research on microbiome-based therapies, microbiota, probiotics, and the wide range of health conditions it can influence.
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持続可能性

R&D Insights: Tiny microplastics with massive implications

Microplastic pollution is a global problem due to their disruption of ecosystems and their ingestion by humans and animals.
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バイオテクノロジー

Exosomes, the rising star of therapeutics: Infographic

Exosomes are reshaping the future of drug delivery, therapeutics, and diagnostics. Learn about exosomes and the challenges with the technology.
|インフォグラフィック
バイオテクノロジー

R&D Insights: 3D printing in biomedical applications

3D printing has major biomedical applications. See the new technologies that are reshaping personalized healthcare.
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合成化学

Synthetic organic chemistry: Peer-reviewed landscape publication

This article, published in collaboration with the National Natural Science Foundation of China, the Chinese Academy of Sciences, and CAS, examines the state of global synthetic organic chemistry research with a focus on enzyme catalysis, photocatalysis, and green chemistry.
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合成化学

Top emerging trends in synthetic organic chemistry

CAS and the Chinese Academy of Sciences explore hidden connections and publication trends in synthetic organic chemistry.
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持続可能性

R&D Insights: Sustainable agriculture and fertilizer production

Agriculture and fertilizers have a sustainability problem. Understand emerging trends around reducing this industry's carbon emissions.
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安全性

The science behind dioxins, vinyl chloride, and proven remediations

Incidents like the East Palestine chemical spill have led researchers to reevaluating the safety of transporting hazardous materials.
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バイオテクノロジー

R&D Insights: Exosomes in drug delivery and diagnostics

The expansion of exosome research has led to significant clinical advancements, and new approaches to drug delivery and diagnostics.
|エグゼクティブサマリー
バイオテクノロジー

ポリマーから義肢まで - 生物医学における3Dプリンティングの発展

From prosthetic ears to artificial organs, learn about the latest trends and innovations in 3D printing in biomedicine.
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バイオテクノロジー

Explore biomedicine’s 3D printing scientific journal review

The possibilities of 3D printing in biomedicine are nearly limitless, as evidenced by this journal publication.
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新興の科学分野

2023年最大の科学のブレークスルーと最新トレンド

2023年のイノベーションを加速させる最新の科学と最先端の研究で、常に一歩先の情報を確認ください。
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持続可能性

Hydrogen fuel-Insights into a growing market

Hydrogen fuel technology is being examined for powering electricity, heating, and transportation.
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持続可能性

Scientific review on sustainable fertilizers

We analyze the scientific and patent trends on sustainable fertilizers in the CAS Content Collection to help scientists use new, more environmentally friendly sources.
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持続可能性

Innovation in sustainable fertilizer production

Synthetic fertilizers ae valuable but leave a large carbon footprint. Sustainable fertilizers are an environmentally friendly alternative that is growing in interest.
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持続可能性

Scientific review on microplastics pollution

Methods to push back against the wave of microplastics that are poisoning the environment are in full swing.
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持続可能性

Microplastics: Tackling the invisible enemy

Microplastics come from countless sources and have a large impact on the environment. Scientists are working hard to combat this growing problem.
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創薬

Expedited FDA designation of breakthrough therapy

The FDA can designate drug candidates as “breakthrough therapies” (breakthrough therapy designation or BTD) for certain drug candidates that demonstrate substantial improvement over available therapies on a clinically significant endpoint.
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バイオテクノロジー

Exosomes – nature's lipid nanoparticle, a rising star in drug delivery and diagnostics

Exosomes – nature's lipid nanoparticle, a rising star in drug delivery and diagnostics
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バイオテクノロジー

Exosomes: Reshaping drug delivery and diagnostics

Exosomes are nature’s lipid nanoparticles and their unique physical properties will unlock new applications in drug development, delivery and diagnostic applications in the future
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創薬

Bioorthogonal chemistry and its applications

Bioorthogonal chemistry is a set of methods that use the chemistry of non-native functional groups to analyze biology in living organisms.
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新興の科学分野

Key insights on click chemistry and bioorthogonal chemistry

Learn about the basics of click chemistry and bioorthogonal chemistry that was recently awarded the 2022 Nobel Prize in Chemistry. Read about emerging trends, insights on publication trends, and future applications of bioorthogonal chemistry.
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新興の科学分野

Infographic - Bioorthogonal Chemistry's Path to the Nobel Prize

Timeline showing key reactions and applications culminating in 2022 Nobel Prize in Chemistry
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創薬

How mRNA COVID-19 vaccines work to fight COVID-19

When mRNA (messenger RNA) vaccines are injected into a patient, tiny lipid vesicles transport mRNA molecules through the body fluids and merge with immune cells, called antigen-presenting cells (APCs).
|ビデオ
創薬

Targeting ACE2 for treatments of COVID-19

Scientists are searching ways to stop the spread of COVID-19, and the ACE2 receptor is one of the most promising targets.
|ビデオ
持続可能性

よりグリーンなプラスチック代替品、バイオベースポリマー

With over 90% of the world’s plastics production requiring fossil fuels, bio-based polymers generated from renewable sources have substantial benefits over traditional plastics – from reducing CO2 emissions, increased biodegradability, and less dependence on fossil fuels. Learn more in our landscape
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持続可能性

Lithium ion battery recycling

Learn more about the scientific challenges, emerging technologies, and the financial and environmental implications for recycling lithium ion batteries.
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創薬

Bioorthogonal chemistry: A review of its diverse applications in science and medicine

Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional groups to explore and understand biology in living organisms.
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デジタル研究開発

Addressing sustainability of the global patent system: the role of AI in enhancing productivity

This whitepaper explores challenges and opportunities for worldwide patent offices as they seek to ensure sustainability and future growth. It focuses on the application of artificial intelligence-enabled workflow solutions to enhance productivity and patent quality.
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デジタル研究開発

Predicting new chemistry: Impact of high-quality training data on prediction of reaction outcomes

Scientists at Bayer expand their understanding into new, useful chemistry by improving the predictive power of a synthesis planning model with scientist-curated reactions from CAS.
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創薬

Accelerating Discovery: COVID-19 Vaccine Breakthroughs and their Future Impact

This insight report explores innovative research and technologies that played crucial roles in Covid-19 vaccine development.
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創薬

Accelerating discovery: COVID-19 vaccine breakthroughs and their future impact

This insight report explores innovative research and technologies that played crucial roles in Covid-19 vaccine development.
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創薬

How molecular glues are connecting targeted protein degradation to the clinic

Targeted protein degradation is a novel and quickly expanding drug discovery strategy. It is a new way of utilizing disease-causing proteins to attack severe illnesses, which has the potential to be used among more serious illnesses, such as cancer or neurodegenerative diseases.
|ジャーナル
創薬

The Landscape of Artificial Intelligence in Chemistry and Opportunities for Growth

Artificial intelligence (AI) and machine learning have been growing exponentially over the last decade, but how has the field of Chemistry evolved with this emerging trend?
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創薬

RNA-Derived Medicines: A review of the research trends and developments

The use of RNA in therapeutics has the potential to revolutionize medicine. This white paper highlights the emerging trends in the industry.
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創薬

Lipid Nanoparticles: Past, Present, and Future Opportunities

Lipid nanoparticles play critical roles in mRNA vaccines for treating COVID-19, but their use is not new. Read about past, present, and future opportunities.
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創薬

The progress and promise of RNA medicine─An arsenal of targeted treatments

The last decade has seen a dramatic shift towards RNA-based medicine. Rapid success in developing lipid-RNA nanoparticles for COVID-19 mRNA vaccines, along with several approved drugs, has propelled RNA to the forefront of pharmaceutical research and development. Explore this revolutionary trend.
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持続可能性

A review of materials research for a green hydrogen economy

Many technologies have been researched with an eye toward enabling a hydrogen economy.
|ジャーナル
持続可能性

Bio-based polymers as an alternative to fossil fuel plastics

Most synthetic polymers are derived from fossil fuel resources, whose scarcity and imbalanced global distribution can affect plastics producers. Bio-based polymers, obtained from renewable biomass resources, have received wide attention in the past two decades.
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創薬

Knowledge graphs accelerate COVID-19 therapies

This white paper details the CAS Biomedical Knowledge Graph and shows how it was used in drug discovery for COVID-19.
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持続可能性

How scientists are restoring carbon balance in the environment

While human capabilities have only increased due to recent technological and medical advances, they have significantly contributed to the release of around 830 gigatons of CO2 into the atmosphere in just the last 30 years alone.
|ジャーナル
バイオテクノロジー

Intrinsically disordered proteins: perspective on COVID-19 infection and drug discovery

It turns out that these intrinsically disordered proteins may be the key to better overcoming diseases in neurodegeneration, diabetes, cardiovascular disease, amyloidosis, genetic diseases, and cancer.
|ジャーナル
持続可能性

Readdressing the balance: Exploring research trends in carbon dioxide sequestration

Learn more about carbon capture, storage, and reduction in our landscape view of this emerging research with unique insights.
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持続可能性

The regulatory environment for lithium-ion battery recycling

Lithium-ion batteries (LIBs) are commonly used in a variety of consumer products, including cellular phones, laptop computers, and more recently, electric and hybrid vehicles.
|ジャーナル
持続可能性

Lithium-ion battery recycling: Overview of techniques and trends

As the production and usage of lithium-ion batteries (LIBs) has increased exponentially, their manufacturing and disposal have become subjects of political and environmental concerns.
|ジャーナル
創薬

Knowledge graph-based approaches to drug repurposing for COVID-19

The COVID-19 pandemic has motivated researchers across the globe to find effective drugs and therapeutics for treating the disease.
|ジャーナル
創薬

Artificial intelligence in chemistry: Current trends and future directions

In recent years, AI application to chemistry has rapidly grown. While there has been numerous publicity about AI used in this manner, there hasn’t been a lot of in-depth analysis on its use and development in the chemistry field.
|ジャーナル
創薬

The research landscape and advancement of lipid nanoparticles

Lipid nanoparticles (LNPs) have emerged as promising vehicles to deliver a variety of therapeutics in the pharmaceutical industry. Liposomal drugs, based on an earlier version of LNPs, have already been approved and applied to medical practice.
|ジャーナル
創薬

A review of the global efforts on COVID-19 vaccine development

This report reviews Covid-19 vaccine research, compares the underlying technologies, the use of adjuvants and delivery systems in their application, and provides a perspective on their future direction.
|ジャーナル
安全性

Ammonium nitrate safety

This in-depth CAS Insights Report discusses the chemical properties of ammonium nitrate, its hazards and safety rules, and provides a useful resource for those involved in the handling and storage of this compound.
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