Induced-proximity target protein degradation (TPD) is a ground-breaking strategy in drug discovery that has emerged in the last decade. This CAS white paper surveys the research landscape, status of clinical trials, and discusses possible future opportunities.
With the widely publicized carbon emissions “race to zero” target by 2050 – interest has been increasing in carbon capture, storage and reduction technologies. Learn more in our landscape view of this emerging research with unique insights and a look at future opportunities.
The use of RNA in therapeutics has the potential to revolutionize medicine. This white paper highlights emerging trends in targets, chemical modifications, and new delivery systems that increase stability of RNA.
Read our white paper to find out more about the advantages, limitations, and popularity of the different classes of biopolymers, and how the research and development interest in these alternatives to traditional plastic has changed over the last two decades.
This whitepaper explores challenges and opportunities for worldwide patent offices as they seek to ensure sustainability and future growth. It focuses on the application of artificial intelligence-enabled workflow solutions to enhance productivity and patent quality.
Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional groups to explore and understand biology in living organisms. This review summarizes common reactions used in bioorthogonal methods, their advantages and disadvantages, and their frequency of occurrence in the literature.
This white paper presents an analysis of the RAS inhibitor landscape, with views based on structural similarity, chemical properties, and patent assignees. See what the insights reveal.
October 6, 2021
Asymmetric Organocatalysis: Selective and Sustainable Synthetic Chemistry Solution Wins 2021 Chemistry Nobel
Benjamin List and David W.C. MacMillan were awarded the 2021 Nobel Prize in Chemistry for their development of a precise new tool for molecular construction: organocatalysis. This has had a great impact on pharmaceutical research, and has made chemistry greener.