CAS Insights™

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Emerging trends in chemical spills: vinyl chloride, dioxins and remediations
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Idea in brief:  exosomes to reshape drug delivery and diagnostics
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Safety
The science behind dioxins, vinyl chloride, and proven remediations
Discover the science behind vinyl chloride, dioxins and different remediations being developed. Explore the latest patent trends, research publications, and data challenges surrounding dioxins and...

Article

Exosome-acs-webinar
Biotechnology
ACS Webinar on Nature’s Lipid Nanoparticles: Exosomes
Discover how exosomes, nature's lipid nanoparticles, are reshaping drug delivery and treatment of diseases from cancer to cardiovascular disease and beyond. Learn from experts at Mayo Clinic, Direct...

Webinar

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Biotechnology
RNA medicines: what technologies are investors funding?
Learn about market trends in the RNA medicine space and what technological approaches and indications investors are backing.

Article

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Biotechnology
R&D Insights: exosomes in drug delivery and diagnostics
For the executive who needs to quickly understand emerging trends around exosomes, lipid nanoparticles, and their impact on drug delivery, diagnostics, and therapeutics this idea in brief will provide...

Executive Summary

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Sustainability
New advances in recycling of lithium-ion batteries
Learn about the latest advancements in lithium-ion battery recycling technology in this article. Discover a new approach for direct recycling that could make it possible to repair and reuse depleted...

Article

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Biotechnology
From polymers to prosthetics: the growth of 3D printing in biomedicine
Explore the limitless potential of 3D printing in biomedicine with this in-depth report. From prosthetic ears to artificial organs, learn about the latest trends and innovations. Discover the...

Insight Reports

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Biotechnology
Explore biomedicine’s 3D printing scientific journal review
Explore the possibilities of 3D printing in biomedicine with this analysis from a scientific journal. From the production of tissues and organs to personalized prostheses and medications, learn about...

Journal Publication

3D Printing Blog HERO
Biotechnology
Trends and innovations in biomedical 3D printing
Discover the innovative applications of biomedical 3D printing, starting with from a short history of the technology, all the way to the latest trends of 3D printing in healthcare.

Article

Nuclear Energy
Sustainability
Is nuclear energy critical in solving climate change?
Recent advances in the design of nuclear reactors have improved both their energy production efficiency and safety. The CAS Content Collection shows a significant increase in patent and journal...

Article

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Emerging Science
Top scientific breakthroughs and emerging trends for 2023
Stay ahead of the curve with the latest in emerging science and cutting-edge research that is accelerating the landscape of innovation. From new discoveries in synthetic biology to breakthroughs in...

Article

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Sustainability
Innovation in sustainable fertilizer production
Detailed landscape report on the latest trends in sustainable agriculture and fertilizer production, new opportunities and insights on the scientific advancements that will enable future innovation

Insight Reports

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Sustainability
Scientific review on sustainable fertilizers
Scientific journal review examines and analyzes the scientific and patent publication trends so the scientific community understands key breakthroughs to build upon, emerging compounds, and the...

Journal Publication

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Sustainability
Reduce, reuse, recycle: the path to sustainable agriculture
Explore the path to sustainable agriculture and learn about the key role it plays in global food production. Discover how reducing, reusing, and recycling can improve fertilizer access, minimize...

Article

microplastics-article-cas-insights-article
Sustainability
Are we doing enough to solve the major issue of microplastics?
Understand the environmental threat of microplastics by exploring its impact through resources such as the 2022 WHO report on dietary and inhalation exposure to microplastics, and microplastics...

Article

Microplastics tackling the invisible enemy
Sustainability
Microplastics: tackling the invisible enemy
In-depth, detailed landscape report that reveals new approaches, publication trends, and ideas gaining traction in the fight against microplastics pollution.

Insight Reports

microplastics-journal
Sustainability
Scientific review on microplastics pollution
Scientific journal review detailing the emerging landscape of microplastics research, publication, and patent trends. This analysis highlights new opportunities and challenges facing humanity that is...

Journal Publication

Targeting a Potentially Important Receptor in Disease Pathogenesis
Drug Discovery
ACE2: Targeting a Potentially Important Receptor in Disease Pathogenesis
Learn more about ACE2 the critical protein that remains the critical target of COVID-19 and so many additional viral infections. This overviews emerging trends and insights on publications,...

Article

Exosome CAS Insights article 3
Drug Discovery
Exosome research: from platelet dust to pioneering therapeutics
Landscape view of emerging contributors, companies, and researchers in the emerging field of exosome research. This article overviews key players in diagnostics and therapeutic fields of exosome...

Article

Exosome hero article 2
Drug Discovery
Exosome therapy and diagnostics: the path to becoming clinical giants
Exosomes’ unique physical properties could unlock massive changes in the fields of drug delivery and diagnostics. However, the biggest challenge for exosomes is the methodologies of isolation and...

Article

Breakthrough therapy
Drug Discovery
Expedited FDA designation of breakthrough therapy
The FDA can designate drug candidates as “breakthrough therapies” (breakthrough therapy designation or BTD) for certain drug candidates that demonstrate substantial improvement over available...

Infographic

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Biotechnology
Exosomes – nature's lipid nanoparticle, a rising star in drug delivery and diagnostics
Exosomes – nature's lipid nanoparticle, a rising star in drug delivery and diagnostics

Journal Publication

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Biotechnology
Exosomes: Reshaping drug delivery and diagnostics
Exosomes are nature’s lipid nanoparticles and their unique physical properties will unlock new applications in drug development, delivery and diagnostic applications in the future

Insight Reports

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Biotechnology
The evolving exosome: from small player to rising star
A historical overview of the discovery of exosomes, key milestones in their rise, and why they will revolutionize the diagnostic and drug delivery fields in the future.

Article

Ammonium Nitrate Hero
Safety
Ammonium nitrate: making it safer today for a better tomorrow
Ammonium nitrate has the power to feed billions, yet when stored improperly is like a bomb waiting to happen. How can we make this fertilizer safer? Learn about emerging science, safer alternatives,...

Article

cas-insights-nanoparticles
Drug Discovery
The therapeutic potential of nanotechnology beyond COVID-19
Learn more about lipid nanoparticles, their origin, role in COVID vaccines, and future applications. This overviews emerging trends and insights on publications, milestones, and future applications in...

Article

cytokines in severe COVID-19
Drug Discovery
Cytokine storm warning: The critical role of cytokines in immunity and infection
Learn more about cytokine storms and their role in both immunity and severe infection with COVID-19 and additional viral infections. This overviews emerging trends and insights on publications,...

Article

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Sustainability
Hidden greenhouse gas emissions in plant growth 
Learn more about the hidden greenhouse gas emissions of plants, a more sustainable approach to fertilizer production, and new approaches to make phosphorus more recyclable.

Article

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Digital R&D
Predictive chemical deformulation flips the formulation challenge
Deformulation is the process of reverse-engineering the composition of known formulations. This publication shows the value of consistent and highly structured representations in predictive models.

Journal Publication

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Sustainability
Emerging market and science trends in sustainable fertilizers production
If you are producing fertilizers, phosphates, or any of our critical agricultural products, you know sustainability is a big challenge. Join us for the latest in phosphate recycling, sustainable...

Webinar

cas data space knowledge management
Digital R&D
Dark data in R&D: How knowledge management can uncover hidden value
Research and development teams amass huge quantities of complex data which, if exploited correctly, can be a useful information source to improve decision-making and drive innovation.

Article

Nuclear Energy Infographic
Sustainability
Nuclear energy could be the key to cutting global emissions
Visual infographic of nuclear energy’s key benefits of an efficient fuel source, a low emissions option (compared to coal and natural gas) and new recycling efforts that minimize nuclear waste.

Infographic

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Drug Discovery
ACS webinar on molecular glues and targeted protein degradation
Learn more about the expert panel discussion on molecular glues and targeted protein degradation. Expert panelists include Dr. Benjamin Ebert, the chair of Medical Oncology at the Dana-Farber...

Webinar

bioorthogonal chemistry nobel prize
Emerging Science
Infographic - Bioorthogonal Chemistry's Path to the Nobel Prize
Timeline showing key reactions and applications culminating in 2022 Nobel Prize in Chemistry

Infographic

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Emerging Science
Key Insights on Click Chemistry and Bioorthogonal Chemistry
Learn about the basics of click chemistry and bioorthogonal chemistry that was recently awarded the 2022 Nobel Prize in Chemistry. Read about emerging trends, insights on publication trends, and...

Article

How MRNA Covid 19 vaccines work
Drug Discovery
How mRNA COVID-19 Vaccines Work to Fight COVID-19
When mRNA (messenger RNA) vaccines are injected into a patient, tiny lipid vesicles transport mRNA molecules through the body fluids and merge with immune cells, called antigen-presenting cells...

Video

Digital R&D
The rise of AI drug development technology
"When you’re finished changing, you’re finished." Business leaders likely weren't the intended audience when Benjamin Franklin uttered his now famous quote. However, his words likely resonate...

Article

Drug Discovery
Breakthrough Therapy Designation: The Real-World Impact of Structural Novelty
Find out how companies improve their prediction accuracy, obtain Breakthrough Technology Status and shorten the development and review time of new drugs by leveraging CAS advanced machine learning...

Article

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Sustainability
Green Chemistry in the Pharma Industry: Sustainable Pastures for Those Who Innovate
One approach that has gained momentum since the 1990s is green chemistry, a scientific field focused on "the invention, design, and application of chemical products and processes to reduce or...

Article

Neural network artificial intelligence
Drug Discovery
AI drug discovery: assessing the first AI-designed drug candidates to go into human clinical trials
This blog details the recently published CAS indicator of drug innovation based on the structural novelty of new molecular entities (NMEs) which may better assess innovativeness of new drugs.

Article

targeting-ace2-for-treatments
Drug Discovery
Targeting ACE2 For Treatments of COVID-19
Targeting ACE2 For Treatments of COVID-19

Video

Hero image bioorthogonal chemistry white paper
Drug Discovery
Bioorthogonal Chemistry: A Review of Its Diverse Applications in Science and Medicine
Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional groups to explore and understand biology in living organisms. This review summarizes common reactions used in...

Insight Reports

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Digital R&D
Predicting New Chemistry: Impact of High-Quality Training Data on Prediction of Reaction Outcomes
Scientists at Bayer expand their understanding into new, useful chemistry by improving the predictive power of a synthesis planning model with scientist-curated reactions from CAS.

Insight Reports

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Sustainability
Lithium Ion Battery Recycling
Learn more about the scientific challenges, emerging technologies, and the financial and environmental implications for recycling lithium ion batteries.

Insight Reports

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Sustainability
Bio-based Polymers: A Green Alternative to Traditional Plastics
Read our white paper to find out more about the advantages, limitations, and popularity of the different classes of biopolymers, and how the research and development interest in these alternatives to...

Insight Reports

Global Patent System Sustainability white paper thumbnail image
Digital R&D
Addressing Sustainability of the Global Patent System: The Role of AI in Enhancing Productivity
This whitepaper explores challenges and opportunities for worldwide patent offices as they seek to ensure sustainability and future growth. It focuses on the application of artificial...

Insight Reports

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Drug Discovery
Accelerating Discovery: COVID-19 Vaccine Breakthroughs and their Future Impact
This insight report explores innovative research and technologies that played crucial roles in Covid-19 vaccine development.

Insight Reports

Space food for Artemis blog astronaut image
Emerging Science
Space Food for Artemis Has Real-World Applications
NASA’s Artemis Program has also focused attention on topics such as food safety, reliability, and nutrition in space. This blog touches on novel approaches to these problems like 3D printed space...

Article

cover image for blog about RAS oncoprotein inhibitors in treating cancers
Drug Discovery
Emerging trends in targeting "undruggable" RAS proteins for cancer treatment
It is estimated that one in five human cancers involve RAS mutations. Although once considered undruggable, this blog looks at recent advances in RAS inhibitors and emerging therapies.

Article

Biotechnology
The long road to success: Refining the next generation of mRNA vaccines
mRNA vaccines have many potential advantages over conventional vaccines in mitigating the spread and eventually ending the COVID-19 pandemic. Learn more about mRNA vaccines and how CAS is committed to...

Article

picture of surgical mask
Drug Discovery
With COVID BA.5 and BA.2.75 Variants, Are Masks Back in?
The COVID pandemic revealed deficiencies in mask development and production. Innovation will be crucial in slowing the spread of new variants of the virus. There are many factors that can be improved...

Article

depiction of spike protein region on a Covid virus
Drug Discovery
Why the Omicron BA.5 Variant Evades Vaccines
As COVID-19 cases rise again worldwide, the Omicron subvariant BA.5 is currently the dominant strain. This blog explores some key mutations that increase transmission, evade protective antibodies, and...

Article

molecular-glues-hero-image
Drug Discovery
How Molecular Glues Are Connecting Targeted Protein Degradation to the Clinic
Targeted protein degradation is a novel and quickly expanding drug discovery strategy. It is a new way of utilizing disease-causing proteins to attack severe illnesses, which has the potential to be...

Journal Publication

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Drug Discovery
The Landscape of Artificial Intelligence in Chemistry and Opportunities for Growth
Artificial intelligence (AI) and machine learning have been growing exponentially over the last decade, but how has the field of Chemistry evolved with this emerging trend?

Insight Reports

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Biotechnology
Molecular glues and induced proximity: solving the undruggable
Molecular glues have been used to uncover new therapeutic agents. Because of their targeted protein degradation that holds them together, these glues have exciting potential in uncovering new drugs to...

Article

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Drug Discovery
RNA-Derived Medicines: A review of the research trends and developments
The use of RNA in therapeutics has the potential to revolutionize medicine. This white paper highlights the emerging trends in the industry.

Insight Reports

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Drug Discovery
Lipid Nanoparticles: Past, Present, and Future Opportunities
Lipid nanoparticles play critical roles in mRNA vaccines for treating COVID-19, but their use is not new. Read about past, present, and future opportunities.

Insight Reports

Monkeypox virus cellular depiction
Emerging Science
Monkeypox: scientifically, how worried should we be?
With recent headlines on monkeypox, learn more about the research landscape, scientific profiles, and currently available therapies. A deeper understanding of the published science enables clarity...

Article

trees are an important source of carbon capture and storage
Sustainability
Combatting carbon emissions: Is carbon capture the answer?
This blog summarizes the results of an extensive literature review of the CAS Content Collection detailing terms related to carbon capture, including methods employed, storage, or conversion, which...

Article

rna-medicine-hero-image
Drug Discovery
The Progress and Promise of RNA Medicine─An Arsenal of Targeted Treatments
In the past decade, there has been a shift in research, clinical development, and commercial activity to utilize RNA for medicine. With the rapid success in the development of lipid–RNA...

Journal Publication

photo showing sample vials of RNA based therapeutics
Biotechnology
A therapeutic revolution: RNA in COVID-19 and beyond
We are in the midst of a therapeutic revolution, according to the authors of a recent review article in Frontiers in Bioengineering and Biotechnology. They were commenting on the rapid expansion of...

Article

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Materials
Biopolymers: manufacturing’s latest green hero?
Plastics found in common consumer products are traditionally made from synthetic polymers derived from petroleum. Biopolymers created from biomass are generated from renewable sources, which fixes...

Article

Green Hydrogen Blog thumbnail image
Sustainability
Green hydrogen economy: game-changing technologies to transform the world’s energy supply
A literature search in the CAS Content Collection provides useful insights into recent and ongoing intensive research and development into green hydrogen production, storage, and utilization in fuel...

Article

CAS Green Hydrogen White Paper thumbnail
Sustainability
A Review of Materials Research for a Green Hydrogen Economy
Many technologies have been researched with an eye toward enabling a hydrogen economy. In the field of hydron utilization in fuel cells, numerous materials have been created to target higher...

Journal Publication

bio-based-polymers-hero-image
Sustainability
Bio-Based Polymers As An Alternative to Fossil Fuel Plastics
Most synthetic polymers are derived from fossil fuel resources, whose scarcity and imbalanced global distribution can affect plastics producers. Bio-based polymers, obtained from renewable biomass...

Journal Publication

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Drug Discovery
Knowledge Graphs Accelerate COVID-19 Therapies
This white paper details the CAS Biomedical Knowledge Graph and shows how it was used in drug discovery for COVID-19.

Insight Reports

carbon-capture-hero-image
Sustainability
How Scientists are Restoring Carbon Balance in the Environment
While human capabilities have only increased due to recent technological and medical advances, they have significantly contributed to the release of around 830 gigatons of CO2 into the atmosphere in...

Journal Publication

artificial intelligence in patent workflow solutions
Intellectual Property
AI proves effective at improving patent office efficiency and application timeliness
Discover how artificial intelligence (AI) reduces patent application delays, increases patent quality, and optimizes patent office efficiency.

Article

photo depicting a protein structure and folding
Drug Discovery
Are intrinsically disordered proteins the key to treating COVID-19?
Learn about the important functions of intrinsically disordered proteins and the key role they play in COVID-19 therapy.

Article

peptides-proteins-hero-image
Biotechnology
Intrinsically Disordered Proteins: Perspective on COVID-19 Infection and Drug Discovery
It turns out that these intrinsically disordered proteins may be the key to better overcoming diseases in neurodegeneration, diabetes, cardiovascular disease, amyloidosis, genetic diseases, and...

Journal Publication

photo of child being vaccinated
Drug Discovery
COVID vaccine ingredients for children under 5
This blog lists and discusses the common ingredients (both in the household and scientific contexts) as well as the unique ingredients used in the Covid-19 vaccines currently in use in the United...

Article

picture of car being fueled with hydrogen
Sustainability
A greener future: Lithium-ion batteries and Hydrogen fuel cells
In the ongoing pursuit of greener energy sources, lithium-ion batteries and hydrogen fuel cells are two technologies that are in the middle of research boons and growing public interest. Read this...

Article

picture of brain
Emerging Science
How Your Gut Microbiome is Linked to Depression and Anxiety
Gut microbiota, gut flora, or microbiome are the microorganisms that live in the digestive tracts of humans and other animals. While some bacteria are associated with disease, others are particularly...

Article

cannabinoid compounds as potential therapeutics
Consumer Goods
The scientific trends of cannabinoid research
This blog is focused on lesser-known cannabinoids, their key medicinal benefits discussed in the scientific literature, and a deeper view into their chemical structures.

Article

carbon capture hero image 2
Sustainability
The Regulatory Environment for Lithium-Ion Battery Recycling
Lithium-ion batteries (LIBs) are commonly used in a variety of consumer products, including cellular phones, laptop computers, and more recently, electric and hybrid vehicles.

Journal Publication

lithium-ion batteries
Sustainability
Lithium-Ion Battery Recycling─Overview of Techniques and Trends
As the production and usage of lithium-ion batteries (LIBs) has increased exponentially, their manufacturing and disposal have become subjects of political and environmental concerns.

Journal Publication

lithium ion battery recycling
Materials
The next growth wave: lithium-ion battery recycling technologies
Find out more about lithium-ion battery recycling processes, emerging trends and global challenges.

Article

Bioorthogonal chemistry glycan depiction
Biotechnology
Bioorthogonal chemistry: exploring the importance of sugars in the cell
Bioorthogonal chemistry has a wide range of applications in science and medicine, and has been used to progress research significantly in recent years. In addition to propelling the field of...

Article

bioorthogonal chemistry hero image
Drug Discovery
Bioorthogonal Chemistry and Its Applications
Bioorthogonal chemistry is a set of methods that use the chemistry of non-native functional groups to analyze biology in living organisms.

Journal Publication

COVID Omicron variant illustration
Drug Discovery
Omicron variant accelerates need for more diverse COVID-19 vaccine strategy
Preliminary study of the Omicron variant indicates that it has evolved significantly from the original version of the virus first identified in China in 2019, which means there is an increased...

Article

Pyschedelics for treating PTSD - blog hero image
Emerging Science
Are psychedelics next to treat depression and PTSD?
Recent clinical trials show that psychedelics like LSD, MDMA, and Psilocybin - when properly controlled for dosing and administration - are having positive outcomes in treating mental health...

Article

machine learning hero image
Digital R&D
Exploring machine learning in chemistry: trends and opportunities
Learn about the growth and barriers of artificial intelligence (AI) and learning algorithms within the field of chemistry.

Article

Nurse administering booster vaccine
Biotechnology
COVID-19 vaccine boosters: what does the research show?
With recent mRNA booster recommendations, many ask if they should get a COVID-19 booster and what the science shows? This blog explains the science of boosters, reviews current recommendations, and...

Article

Use of lipid nanoparticles in cancer therapy
Biotechnology
Lipid Nanoparticles – Key Players in Cancer Treatment
Lipid nanoparticles are key therapeutic vehicles in the pharmaceutical industry, as well as medical imaging, cosmetics, nutrition and more. Discover how lipid nanoparticles are applied in cancer...

Article

microfluidics for improved production of lipid nanoparticles for vaccines
Emerging Science
Tackling the Global Vaccine Distribution Challenge
COVID-19 vaccine production is limited by the output of lipid nanoparticles, but use of microfluidic technology has been successful in producing lipid nanoparticles.

Article

CAS Blog cover image, Weak Bonds – the Hidden Power Within Combustible Chemicals
Safety
Weak Bonds – the Hidden Power Within Combustible Chemicals
To mark the anniversary of the industrial accident and explosion in Beirut, this CAS Insight focuses on the role of ammonium nitrate and how weak bonds in certain chemicals can lead to instability and...

Article

CAS Biomedical Knowledge Graph thumbnail image
Drug Discovery
Exploring Knowledge Graphs for COVID-19 Drug Discovery
The methodology behind CAS knowledge graphs enhances potential drug identification for COVID-19 treatment and other diseases.

Article

knowledge-gap-hero-image
Drug Discovery
Knowledge Graph-Based Approaches to Drug Repurposing for COVID-19
The COVID-19 pandemic has motivated researchers across the globe to find effective drugs and therapeutics for treating the disease.

Journal Publication

performance enhancing drugs CAS blog thumbnail
Emerging Science
The Science Behind Performance-Enhancing Drugs
Performance enhancing drugs are constantly scrutinized, tracked, and tested for by the International Olympic Committee, US Anti-Doping Agency and World Anti-Doping Agency. This blog will provide...

Article

ai-in-chemistry-hero-image
Drug Discovery
Artificial Intelligence in Chemistry: Current Trends and Future Directions
In recent years, AI application to chemistry has rapidly grown. While there has been numerous publicity about AI used in this manner, there hasn’t been a lot of in-depth analysis on its use and...

Journal Publication

lipid-nanoparticles-hero-image
Drug Discovery
The Research Landscape and Advancement of Lipid Nanoparticles
Lipid nanoparticles (LNPs) have emerged as promising vehicles to deliver a variety of therapeutics in the pharmaceutical industry. Liposomal drugs, based on an earlier version of LNPs, have already...

Journal Publication

covid-19-vaccine-development-review-image
Drug Discovery
A Review of the Global Efforts on COVID-19 Vaccine Development
This report reviews Covid-19 vaccine research, compares the underlying technologies, the use of adjuvants and delivery systems in their application, and provides a perspective on their future...

Journal Publication

Safety
Safety in numbers: Connecting the community to improve lab safety
The Pistoia Alliance Chemical Safety Library (CSL) is an open-access database providing access to hazardous reaction information crowd-sourced from academic, industry, and government institutions...

Article

Sustainability
Can plastic eating super-enzymes solve our destructive plastic problem?
An overview of research on how microbial enzymes can break down plastics, which could otherwise take hundreds of years to degrade.

Article

picture of crystalline ammonium nitrate
Safety
Ammonium Nitrate Safety
This in-depth CAS Insights Report discusses the chemical properties of ammonium nitrate, its hazards and safety rules, and provides a useful resource for those involved in the handling and storage of...

Insight Reports

hero image for digital transformation white paper
Drug Discovery
Building A Foundation For Profitable Digital Transformation in Sci-Tech R&D
Artificial Intelligence may be hot right now, but the smart money is investing in data. See how CAS solutions can help.

Insight Reports

covid-19-targets-qsar
Drug Discovery
QSAR Machine Learning Models and their Applications for Identifying Potential COVID-19 Therapeutics
To identify potential anti-SARS-CoV-2 therapeutics, CAS scientists are building machine-learning predictive models to identify novel drug candidates for the viral targets 3 chymotrypsin-like protease...

Journal Publication

Drug Discovery
Seeking COVID-19 Therapeutic Candidates with a Computational Approach
Learn how machine learning procedures and CAS COVID-19 resources, including scientific insights, open access datasets and special reports are assisting in the research to fight against COVID-19.

Article

Drug Discovery
Taking aim at COVID-19’s most wanted targets
In support of ongoing research efforts to identify additional drugs for COVID-19, a team of CAS scientists analyzed published scientific information and created a comprehensive report focusing on...

Article

Drug Discovery
Potential therapeutic agents and associated bioassay data for COVID-19 and related human coronavirus infections
To support ongoing research and development of COVID-19 therapeutics, this report provides an overview of protein targets and corresponding potential drug candidates with bioassay and...

Journal Publication

CAS Journal RNAi
Biotechnology
Protecting and Commercializing the Promise of RNAi
In this article from The Patent Lawyer Magazine, Anne Marie Clark, Senior Search Analyst for CAS, discusses how to avoid patent pitfalls as the market for RNAi-derived therapeutics grows.

Journal Publication

Viral spike-protein structure depiction
Drug Discovery
The enemy within: How SARS-CoV-2 uses our own proteins to infect our cells
A critical step in the race to develop treatments for COVID-19 is to gain a clear understanding of how the virus enters our cells. This insight will support development of targeted anitviral...

Article

assay-techniques-hero-image
Drug Discovery
Assay Techniques and Test Development for COVID-19 Diagnosis
To provide a better understanding and comparison of the diagnostic tests available in the fight against COVID-19, CAS has produced a report summarizing the basic principles of molecular and...

Journal Publication

covid-19-therapeutic-agents
Drug Discovery
Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
To support R&D on COVID-19, CAS has produced a special report to provide an overview of published scientific information with an emphasis on patents in the CAS content collection. It highlights...

Journal Publication

Brazil Biodiversity
Sustainability
Organizing Vital Data to Unlock Innovation from Brazil’s Biodiversity
While hosting 15-20% of Earth’s biological diversity, a substantial part of Brazil’s abundant biodiversity remains underexplored. A lack of organized information made it exceedingly difficult for...

Article

CAS digital hero image
Intellectual Property
Chemical Space Analytics: Bridging the Gap Between Data and Action
The Journal of Organic Chemistry article "Recent Changes in the Scaffold Diversity of Organic Chemistry As Seen in the CAS Registry" shows the pace of innovation from a structural perspective is...

Journal Publication

smokestacks with emissions and importance of carbon capture
Sustainability
Readdressing the Balance: Exploring Research Trends in Carbon Dioxide Sequestration
Learn more about carbon capture, storage, and reduction in our landscape view of this emerging research with unique insights.

Insight Reports

thumbnail image for Hydrogen Fuel Insights into a Growing Market white paper
Sustainability
Hydrogen Fuel - Insights into a Growing Market
Download this in-depth CAS Market Report to gain insight into the evolution of hydrogen fuel technology, the global innovation landscape, key market trends and potential applications and...

Insight Reports

Molecular glues blog thumbnail
Drug Discovery
Targeted Protein Degradation and Induced Proximity: Molecular Glues Landscape in Drug Discovery
Induced-proximity target protein degradation (TPD) is a ground-breaking strategy in drug discovery that has emerged in the last decade. This CAS white paper surveys the research landscape, status of...

Insight Reports

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