This report reviews Covid-19 vaccine research, compares the underlying technologies, the use of adjuvants and delivery systems in their application, and provides a perspective on their future direction.
Ammonium Nitrate Safety - electronic brochure
Explore this interactive brochure that provides an overview of the chemistry of ammonium nitrate, the key processes in its manufacture, and important guidelines for safer handling and storage.
QSAR Machine Learning Models and their Applications for Identifying Potential COVID-19 Therapeutics
To identify potential anti-SARS-CoV-2 therapeutics, CAS scientists are building machine-learning predictive models to identify novel drug candidates for the viral targets 3 chymotrypsin-like protease (3CLpro) and RNA-dependent RNA polymerase (RdRp).
Potential therapeutic agents and associated bioassay data for COVID-19 and related human coronavirus infections
To support ongoing research and development of COVID-19 therapeutics, this report provides an overview of protein targets and corresponding potential drug candidates with bioassay and structure-activity relationship data found in the scientific and patent literature for COVID-19 or related virus infections.
Protecting and Commercializing the Promise of RNAi
In this article from The Patent Lawyer Magazine, Anne Marie Clark, Senior Search Analyst for CAS, discusses how to avoid patent pitfalls as the market for RNAi-derived therapeutics grows.
Impact of COVID-19: AI and Machine Learning Solutions
As part of the CPhI webinar series, CAS and IQVIA join forces to deliver insights into optimizing Artificial Intelligence and Machine Learning for predictive analytics, clinical trials and drug discovery in response to COVID-19.
Assay Techniques and Test Development for COVID-19 Diagnosis
To provide a better understanding and comparison of the diagnostic tests available in the fight against COVID-19, CAS has produced a report summarizing the basic principles of molecular and serological assays being used in diagnostic tests for SARS-CoV-2. The report highlights recent advancements in testing technologies and provides a high-level view of currently available diagnostic tests.
Getting Started in Data-Driven Chemical and Materials Discovery
Are you just getting started or ramping up machine learning for chemical and materials research? In this webinar, the panelists will discuss how to prepare for a new informatics project by exploring how to build useful data sets, identify missing capabilities, and communicate expectations.
Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
To support R&D on COVID-19, CAS has produced a special report to provide an overview of published scientific information with an emphasis on patents in the CAS content collection. It highlights antiviral strategies involving small molecules and biologics targeting complex molecular interactions involved in coronavirus infection and replication. The drug-repurposing effort documented herein focuses primarily on agents known to be effective against other RNA viruses including SARS-CoV and MERS-CoV.