CAS Newton is an agentic AI powered by the CAS Content Collection. The AI lives within existing CAS solutions to answer your queries with well-sourced, scientific, actionable results in real-time.

CAS Newton is available to existing CAS SciFinder and CAS BioFinder users. The agentic AI is integrated directly into both solutions, allowing you to begin querying once you log in.

Users may encounter daily usage limits in CAS Newton. Please contact your account representative to discuss expanded access for your organization.

No. CAS maintains the confidentiality of user search activity. CAS does not use user search queries for any purpose beyond providing services to that user. User search queries are not shared with other users and is protected against unintended exposure. User data is never sold or shared with other users or outside of CAS.

No. User data is anonymized and aggregated so that we can observe patterns and themes in general user behaviors. For example, we use anonymized and aggregated data to determine how to identify and prioritize product content.

CAS is committed to providing a safe and secure environment for all users, including the responsible use of AI. CAS does not leverage user search queries to build or train AI models. CAS maintains the confidentiality of user search activities in accordance with its Privacy Policy and in a manner consistent with the CAS Ethical Approach to AI.

Any AI-generated output is labeled as such to ensure the user is aware.

CAS employs robust training and testing to avoid hallucinations. Our AI solutions are built by scientists, for scientists, with accuracy at the forefront. They are rigorously trained, tested, and validated by domain experts using real scientific use cases to ensure accurate answers.

In addition, our AI primarily relies on expertly curated and indexed proprietary data rather than broad, unvetted external sources. By grounding outputs in trusted scientific content, we significantly reduce the risk of hallucinations, helping scientists work with confidence.

View our short video tutorials and get started quickly.

CAS Newton, science-smart agentic AI available to CAS BioFinder users, identifies emerging technology trends in biotechnology by synthesizing patents, and peer-reviewed literature into evidence-backed signals across targets, pathways, and modalities. CAS Newton runs these multi-step searches across the CAS Content Collection, which includes more than 150 years of curated chemistry, biology, and intellectual property data, and cites a verifiable source for its findings.

CAS Newton navigates large-scale scientific data repositories through a conversational agent that interprets intent and retains context to help refine queries, and synthesizes results. CAS Newton grounds every answer in the CAS Content Collection, which includes more than 150 years of scientific literature curated by CAS scientists, and links results to a verifiable source.

CAS Newton streamlines routine scientific literature reviews by searching large reference sets to provide relevant information complete with citations for easy review and validation. CAS Newton, available to users of CAS SciFinder, CAS BioFinder, and CAS IP Finder, grounds every answer with information found in the CAS Content Collection.

Robust scientific data management accelerates lead optimization in drug discovery by connecting curated bioactivity, structure-activity, ADME, toxicity, and clinical trials data so teams iterate on candidates with confidence. CAS Newton, available to CAS BioFinder users, draws on the CAS Content Collection, which includes more than 150 years of curated scientific literature, and cites the source-linked evidence behind its optimization decisions.

CAS Newton,science-smart agentic AI available to CAS SciFinder users, improves the speed of chemical research workflows by searching autonomously to quickly uncover hidden relationships and trends without the need for researchers to manually piece together results.  . CAS Newton returns cited, verifiable answers in seconds, grounded in the CAS Content Collection, which includes more than 150 years of curated scientific literature spanning chemistry and biology.

AI agents retrieve verified scientific data from large databases by grounding answers in curated, expert-validated content and citing each source inline. CAS Newton, science-smart agentic AI, draws on the CAS Content Collection, which includes more than 150 years of peer-reviewed scientific literature curated by CAS scientists, to return evidence-backed responses across chemistry, biology, and IP.

Easy data management for small biotech startups starts with curated content, a secure deployment boundary, and minimal infrastructure overhead. CAS Newton offers a standalone agentic AI interface and access through CAS BioFinder, operates within a secure application boundary with no cross-user model training, and grounds its answers in the curated CAS Content Collection.

Drug discovery platforms support high-throughput screening and chemical synthesis by linking curated bioactivity, structure-activity, reaction, and properties data in one workflow, helping scientists to minimize potential candidates for high-throughput screening and identify synthesis challenges early. CAS Newton performs structure searches, functional group reactivity, spectra predictions, and properties predictions, grounded in the CAS Content Collection’s curated chemistry and life sciences data.

CAS Newton runs multi-step queries across the large, human-curated CAS Content Collection and returns source-linked, auditable answers. A secure boundary keeps user input out of cross-user model training.

CAS Newton automates chemical structure property prediction tasks by combining structure searches, functional group reactivity, spectra predictions, and properties predictions in one conversational, multi-step workflow. CAS Newton sources its answers from the CAS Content Collection, which includes more than 150 years of curated chemistry data.