Why are new authority constructs necessary for life sciences data?

A conversation with Nicole Stobart, Jeff Wilson, Ph.D., and Mark Schmidt from CAS

Transparent blue capsules each holding intricate structures resembling cells or circuits.

Authority constructs and identifiers have been used by CAS within the chemistry sector for almost 100 years as the cornerstone of our world-leading curating and indexing. Our life sciences team is now creating the same indexing tools for a new industry. In this article, we chat with Nicole Stobart, Senior Capabilities Manager in Life Sciences; Jeff Wilson, Ph.D., Assistant Director, Content Strategy and Authority; and Mark Schmidt, Lead Data Steward, about how they are forging this new path using authority constructs.

CAS: What are authority constructs, and why are they important to life sciences research?

CAS: How would you define data curation at CAS?

CAS: What would you say is the advantage of authority constructs for curation?

CAS: Can AI be leveraged to help create authority constructs or curate with them?

CAS: How is CAS going to approach defining and identifying biological entities?

CAS: Are you using structure or function to create these identities for life sciences?

CAS: How do you plan to tackle the longevity of defining by function when biological function changes over time and with new research?

CAS: What makes CAS the right organization to curate this fragmented data?

CAS: How is what you’re doing different than what’s already been done?

CAS: Have you had any pushback from the other existing databases as you move into this space?

CAS: If had a magic wand to change anything in the drug discovery process, what would you change?