CAS STNext® Coffee Lecture: Specific substances in combinatorial libraries

Combinatorial libraries are critical for IP searches, which is why IP professionals must learn how to use them. These libraries are collections of compounds that have been synthesized through combinations of various reactants with the use of high-throughput techniques. These libraries offer broad chemical diversity and are widely used in drug discovery, materials science, and biotech to identify promising candidates.

• Why combinatorial libraries are important for Prior Art searches.
• How entire compound libraries can be represented in patents, i.e., as Markush structures.
• How to search for substances from these libraries in CAS STNext, particularly in the CAS REGISTRY and MARPAT databases.