CAS Fact Sheet

CAS Provides Scientists and Information Professionals with the World's Largest Collection of Information on Disclosed Chemistry and Related Research.


Columbus, Ohio, U.S.A.

Number of Employees



The American Chemical Society has appointed Manuel (Manny) Guzman as president of CAS, the world’s authority for chemical information. Guzman began his appointment on September 30, 2013. He succeeds Robert J. Massie, who has led CAS—based in Columbus, Ohio—for more than 21 years and who retired at the end of March 2014.


CAS, a division of the American Chemical Society, is dedicated to the ACS vision of improving people's lives through the transforming power of chemistry. The CAS team of highly trained scientists finds, collects, and organizes all publicly disclosed substance information, creating the world's most valuable collection of content that is vital to innovation worldwide. Scientific researchers, patent professionals and business leaders around the world rely on a suite of research solutions from CAS that enables discovery and facilitates workflows to fuel tomorrow’s innovation.

Our Work

Our editorial scientists—speaking 50 languages among them—build the highest-quality and most up-to-date chemical databases in the world, using state-of-the art, proprietary technology systems developed by CAS. They review and intellectually analyze published research from thousands of major scientific journals and patent documents from 63 patent authorities, fully disclosing the new and novel science within.


CAS REGISTRY is the most comprehensive collection of disclosed chemical substance information in the world. The gold standard for substance information, CAS REGISTRY contains more than 129 million unique organic and inorganic substances and more than 67 million sequences. Research collected in REGISTRY covers a broad range of scientific disciplines, including biomedical sciences, chemistry, engineering, materials science and agricultural science, among many others.

When a chemical substance is newly encountered in the literature analyzed by CAS, its molecular structure, chemical name, molecular formula and other identifying information are added to REGISTRY and the substance is assigned a unique CAS Registry Number®. Scientists and researchers around the world rely on the CAS Registry Number as the globally accepted identifier of a chemical substance.

CAplusSM Database

CAS' CAplus database contains more than 45 million patent and journal article references in all areas of organic, macromolecular, applied, physical, inorganic and analytical chemistry and biochemistry. Patent and journal literature date from 1907 to the present, with updates made daily. Patent records meeting CAS selection criteria from nine of the major patent offices worldwide are available online in CAplus within two days of the patents' issue, and are fully indexed by CAS scientists in less than 27 days.

Products and Services

Through a suite of products and services, CAS offers access to its databases covering science, engineering, technology, patents, business information and more. These products are designed to accommodate a wide range of information needs.

  • SciFinder® is the leading research tool for chemists and researchers, providing the essential content and proven results scientists need to increase productivity and make faster breakthroughs. The intuitive, award-winning application offers instant access to the most comprehensive collection of chemical substance and reaction information, including CAS REGISTRY — the gold standard of chemical substance collections. Fortune 500 corporations, more than 2,500 universities, and major government agencies around the world rely on SciFinder to fuel R&D initiatives and foster innovation. And now PatentPak™, a robust new patent workflow solution, offers instant access to hard-to-find chemistry in full-text patents directly in SciFinder.

  • STN® is an online database service that provides global access to published research, journal literature, patents, structures, sequences, properties and other data. STN integrates CAS databases with information from other leading database producers worldwide and is accessed through a suite of products:
    • STN Express® is an interface that provides comprehensive desktop access for experienced online searchers.
    • STN® AnaVist offers sophisticated analysis and visualization software for information professionals.
    • STN® on the WebSM combines the STN command functionality with browser technology.
    • STN® Easy enables researchers to search key STN databases covering sci-tech information and patents for a low fee per search.
  • Science IP® is a CAS search service, staffed by experienced researchers who provide high-quality information retrieval in many areas of science as well as comprehensive patent searches.
  • Common Chemistry is a free, web-based resource offered to the public by CAS in partnership with Wikipedia. The resource contains approximately 7,900 chemicals of widespread and general interest, as well as all 118 elements from the periodic table. Substances in this collection were deemed of general interest, with most substances cited 1,000 or more times in the CAS databases.

CAS Customers

More than 2,500 universities, top Fortune 500 corporations and nearly all major patent offices use CAS products to gain access to CAS databases for the comprehensive, current, reliable data they need to enable scientific discovery.


William A. Noyes founded the CAS organization in 1907 to help scientists benefit from the published work of their colleagues around the world by monitoring, abstracting and indexing the world's chemistry-related literature. The results were printed in the publication Chemical Abstracts (CA).

Over the decades, CAS databases have reflected the progress of science, and its search services have been continually improved to allow research scientists and information professionals to find and use this information to best advantage. CAS revolutionized the scientific discovery process in 1995 by providing researchers direct access to its databases through the introduction of SciFinder. Today, scientists are only seconds from information needed to conduct research through CAS products delivered over the web and through software applications.

CAS Impact

CAS was designated a National Historic Chemical Landmark in 2007 by the American Chemical Society. The designation acknowledges the value of the CAS REGISTRY in scientific discovery as the most comprehensive repository of information in chemistry and related sciences.

The United States Patent Office awards CAS a five-year sole source contract for STN, stating in its solicitation letter that "CAS' STN databases offer the largest collection and depth of chemical and related information compared to other commercial web based databases. In addition, CAS is the only company that has a unique, proprietary, chemical structure searching capability using its STN Express software. No other source can successfully meet the USPTO's requirements."

Careers at CAS

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Contact Us

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    614-447-3700 (Worldwide)
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