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CAS BioFinder Discovery Platform™

Move your drug discovery program to the next stage with comprehensive pharmaceutical data embedded into AI-enhanced predictive technology and analytical visualizations, searchable by ligand, scaffold, protein, and disease.

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Confidently advance drug discovery

Working through the literature to understand disease mechanisms, identify new targets, plan structure-activity relationship studies, and assess the potential for off-target interactions takes time and risks missing key information. The CAS BioFinder Discovery Platform brings together the data and solutions needed across drug discovery workflows, including discovery biology and medicinal chemistry.

CAS BioFinder®

Designed to support the full scope of pre-clinical drug discovery work, CAS BioFinder provides biologists and chemists with the data and tools they need to make faster, more confident recommendations.

Our AI-driven models that predict the bioactivity of unknown ligands, matched molecular pairs analysis visualizations, 3D graphs of nearby chemical spaces, and quick summaries of lengthy biomarker data tables are embedded into a foundation of trusted, interconnected data to provide reliable results.

Life sciences capabilities in CAS SciFinder®

Expand the capabilities of CAS SciFinder with detailed bioactivity data tables, biological sequence searches, and seamless integration with searches in CAS BioFinder.

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"CAS BioFinder provides a centralized database for drug discovery. It tells you everything that’s been published in patents and literature and has associated pharmacology pathways, metabolism, and nearby chemical neighbors. A lot of people in drug discovery are going to different databases for each line function, but CAS BioFinder is a nice way of centralizing that."
— Structural biologist, CAS BioFinder development partner

Enhanced biological data for your drug development success

Well known for small molecule chemistry data, the CAS Content Collection™ now includes a broad range of data types to support biology-based inquiry.

Unlike a standard scientific data aggregator, our scientists take additional steps to enrich data by revealing unique connections. We harmonize, organize, and standardize information from thousands of life sciences journals, nearly 100 global patent authorities, and all leading free and third-party databases.

Discover the world-class data powering this platform.

Explore CAS life sciences data

Answer critical drug discovery questions

CAS BioFinder helps early drug discovery teams prioritize their efforts and make confident, informed investment recommendations.

Find potential new targets for disease treatment.
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Inform research paths with an understanding of the disease's mechanisms and pathways.
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Identify early signals of therapeutic potential in likely targets.
Confirm a target's therapeutic relevance before passing to the chemistry team.
Uncover new targets and indications to repurpose drugs.
Identify ligands that interact in a specific way with a target.
Connect ligand activity to therapeutic potential.
Maximize potency and minimize off-target risks.
Improve druglikeness to optimize effectiveness, safety, and synthetic feasibility.
Learn more about medicinal chemistry workflows in CAS BioFinder

Overcome drug development barriers

Learn what pharmaceutical experts have to say about today’s biggest drug development challenges and opportunities.

Read the articles
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CAS Content team

Bring therapies to life faster with reliable and actionable drug discovery data insights through the CAS BioFinder Discovery Platform. 

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