The CAS Content Collection™

Discover what's inside the CAS Content Collection

Spanning over 150 years of scientific discoveries from around the world published in journals , patents , and a wealth of other sources , the CAS Content Collection provides a comprehensive foundation to inform confident decisions throughout your innovation process.

300 MILLION
Substances
110
Patent authorities
50+
Languages
160 MILLION
reactions

CAS Data overview

Chemistry

The foundational chemical data that underpins discovery:

Substances - CAS REGISTRY®
Chemical formulations
Commercial sources
Reactions
Physical properties and spectra
Methods protocols
Markush
Hazard designation

Life sciences data

Biological and pharmacological data integrated with chemistry

Bioactivity
Proteins
Genes
Clinical trials
Diseases
Drug classification
Biomarkers
Pathways
Interactions
Metabolic processes

Materials data

Specialized data for materials science and engineering:

SRO triplet
Polymer structures and properties
Nanomaterials
Crystal structures
Electronic materials
Composite materials
Material performance data
Processing conditions
Coating and surface data
Two scientists in white lab coats review data on a tablet in a laboratory setting.

Documentation

Access detailed information about CAS coverage, classifications, and indexing standards. Find journal coverage lists, patent classifications, standard abbreviations, and transition guides.
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Regulatory and compliance coverage

CAS data spans hundreds of global regulatory lists, including EU REACH, TSCA, OECD, and the Chemical Weapons Convention. Compliance, legal, and R&D teams get a single, authoritative source for chemical regulatory status worldwide.
Documentation

Coverage, classifications, indexing standards, and more

"It is very challenging for humans to collect accurate data from a vast body of literature and transform it into a structured, AI-ready format… CAS did a great job supporting us."
Co-founder and Vice President
Contract Research Organization

Over a century of scientific knowledge management expertise

For over 100 years, CAS has been developing solutions to make scientific knowledge more accessible and valuable to enable scientific discovery. Now you can engage our unique knowledge management expertise and specialized technologies to help overcome scientific data challenges hindering your R&D workflows.

See our expertise in action
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Your data, enhanced with our expertise

Let us apply our specialized expertise to enhance your proprietary scientific information. Through the CAS Intelligence Hub℠, we help organizations clean and harmonize fragmented datasets, build AI‑ready information assets, and unlock deeper insights across their scientific knowledge.

Learn about CAS Intelligence Hub℠

Real world impact

Two CAS Custom Services brochures highlighting a solution success story about custom-curated machine learning training datasets that accelerate optimization of organic synthesis workflows, featuring scientists working in laboratory settings.

El conjunto de datos de entrenamiento de aprendizaje automático seleccionado acelera la optimización del flujo de trabajo de síntesis orgánica

Robotic arm operating in an advanced automated laboratory or manufacturing environment, surrounded by machinery and transparent processing chambers, with the Chemlex logo visible in the corner.

Estableciendo nuevos estándares para la precisión de predicción de IA con datos de entrenamiento personalizados

Custom knowledge management system reduces search time from hours to minutes

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