CAS SciFinder® enhancements
We know being aware of upcoming enhancements to CAS SciFinder is important to you. To help ensure you are prepared to handle questions you may receive from your users when changes occur, we will provide a preview version of the latest release notes below.
Expect a new set of notes to be posted approximately one week prior to each release, which are scheduled every four weeks. Be aware that there may be an occasional change not included in this preview since they are being prepared before the release is final. As always, final release notes will be added to the What’s New? section in the CAS SciFinder solution in conjunction with the actual release.
Preview of CAS SciFinder Release
October 6, 2025 (Build 25-09)
SearchSense: AI-powered Result Summaries
SearchSense in CAS SciFinder provides further value to customers with AI-powered result summaries. Summaries help users gain a quick overview of the literature space before diving into the data, providing both high-level overviews and more detailed information. Links to the relevant scientific literature are included for users to review the findings.
These summaries are generated by AI models trained by scientists focusing on scientific accuracy and traceable citations.
Summaries are presented for queries that are optimized by SearchSense, and for which there are at least five reference results in the answer set.
Summaries are presented on both the All and References result pages for eligible result sets. A preview is first presented:
Selecting “view all” will expand the window to display the full summary. Additionally, in-depth findings are presented when available with links to the source references. At the bottom of the full summary users are provided with mechanisms to give feedback on the AI-powered summary.
Interactive Retrosynthesis
Retrosynthesis in CAS SciFinder now offers unprecedented speed in generating full retrosynthetic plans with near-instantaneous results, enabling users to get answers faster. User workflows are enhanced with displays of supporting evidence, allowing uninterrupted review of generated plans.
Additionally, Interactive Retrosynthesis provides a streamlined experience for users to refine and tailor the plans to suit their needs with convenient filters.
IP Connections: Sort Indexed Substances by Claim Location
On reference detail pages, indexed substance sorting is now updated to prioritize those substances found in the claims section of patents. This updated sorting helps users focus on the most important substances from the patent in their review.
IP Connections: Increased XLSX Download Limits for Basic Identifiers
Download limits have been increased for the Basic Identifiers and Result Summary options in XLSX file format, allowing users to retrieve more information for their downstream processes. Now, when users export references using the Basic Identifiers or Result Summary templates, XLSX files can contain content from the first 500 reference results.
IP Connections: Enable Workflow Features for Prior Art Discovery Results
Prior Art Discovery in CAS SciFinder is being further enhanced with options to download results, add to Projects, and Save. These workflow features enable users to share results with colleagues, combine with other answer sets, or store the results for further analysis.
IP Connections: Prior Art Analysis Search History Enhancement
Search History entries for Prior Art Analysis have been improved with the display of the patent number in addition to the patent title, making it easier for users to understand which reference was submitted for Prior Art Analysis.
IP Connections: Prior Art Discovery Submission Improvement
The Prior Art Discovery search submission process has been improved to provide better confirmation when a search is successfully submitted. Now, upon submitting a Prior Art Discovery search, the user is directed to the Recent Search History section of the home page in CAS SciFinder to the new Prior Art Discovery entry, which shows the current status of the search.
Structure Search Enhancement: Name to Structure
CAS Draw now supports name to structure, allowing users to easily model compounds into the structure editor from a name.
The text input bar in CAS Draw now supports input from a systematic chemical name:
This new enhancement facilitates easy copy and paste from text-based sources to perform robust, comprehensive structure searches in CAS SciFinder.