CAS Chemical Safety Library™
Access a free database of hazardous reaction information from global academic, industry, and government institutions to enhance chemical safety in your laboratory.
About the CAS Chemical Safety Library
The CAS Chemical Safety Library is a repository for the scientific community to capture and confidentially share hazardous reaction information from real-world laboratory experiences to reduce and prevent incidents. Information in the library is publicly available and uploaded to PubChem.
The repository is overseen by an advisory panel made up of experts from CAS, ACS, and academic, industry, and non-profit organizations worldwide.
Prior to September 1, 2023, the Chemical Safety Library was created and maintained by Pistoia Alliance.
The use of dangerous chemicals in the laboratory can lead to major risks. To prevent related disasters, hazardous reaction incident information must be shared across the global research community. With the CAS Chemical Safety Library:
Search
Learn about hazardous reaction information before you head to the laboratory. Search by CAS Registry Number®, chemical name, SMILES, and more.
Contribute
Help make the library even more valuable to other researchers by submitting your hazardous reaction incident information.
Download
Integrate hazardous reaction information from the library with your internal workflows and knowledge bases.
Cronograma da Chemical Safety Library
Outono de 2016
A apresentação de Mark Manfredi (Bristol Myers Squibb) na ACS Outono de 2016, “Ensuring That Lessons Learned Are Not Forgotten, Leveraging ELN to Transform the Safety Paradigm”, inspirou a criação de um sistema simples e colaborativo para coleta de dados sobre reações perigosas. Além de ser promovida por Ramesh Durvasula (Lilly), a Pistoia Alliance liderou o desenvolvimento da Chemical Safety Library.
Primavera de 2017
As informações sobre reações perigosas da Bristol Myers Squibb foram adicionadas à Pistoia Alliance Chemical Safety Library, que foi então expandida por meio de datathons, hackathons e extração de dados da C&EN Safety Letters e de outras fontes.
Inverno 2018 – Primavera 2020
Um sistema de submissão simplificado ajudou a Pistoia Alliance Chemical Safety Library a alcançar 138 registros. Os dados foram disponibilizados aos usuários por meio de arquivos .csv solicitações de arquivos e toda a biblioteca foi compartilhada com a PubChem (National Library of Medicine).
Verão 2020 - Primavera 2024
O CAS passou a hospedar a Chemical Safety Library da Pistoia Alliance e criou um Painel Consultivo liderado por Carmen Nitsche (The Cambridge Crystallographic Data Centre) e Mark Manfredi (Bristol Myers Squibb) para impulsionar os desenvolvimentos futuros. Foi também estabelecida uma parceria estratégica com a Campus Safety, Health, and Environmental Management Association (CSHEMA), ampliando o alcance para o setor acadêmico. Um protocolo reutilizável de coleção de dados (Chemical Safety Library in a Box) foi desenvolvido através de projetos de mineração de dados com a Purdue University e a University of Minnesota.
Primavera 2024
A Chemical Safety Library in a Box foi implementada na UCLA e promovida na CSHEMA Safety Week. Em março, um datathon foi realizado no ACS Spring 2024 para expandir a coleção de informações. O recurso foi oficialmente renomeado para "CAS Chemical Safety Library" após a transferência de propriedade da Pistoia Alliance para a CAS. Atualmente, a CAS Chemical Safety Library inclui mais de 500 registros.
CAS Chemical Safety Library™ Advisory Panel
The CAS Chemical Safety Library is overseen by an advisory panel of experts from CAS and others in the commercial, academic, and non-profit sectors.
The CAS Chemical Safety Library Advisory Panel also recognizes contributions from:
For questions about the CAS Chemical Safety Library, email csladvisorypanel@cas.org.
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