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CAPLUS COPYRIGHT 2008 ACS on STN
| TITLE:
| Novel dosage form comprising modified-release and immediate-release active ingredients |
| INVENTOR(S):
| Vaya, Navin; Karan, Rajesh Singh; Sadanand, Sunil; Gupta, Vinod Kumar |
| PATENT ASSIGNEE(S):
| India |
| SOURCE:
| U.S. Pat. Appl. Publ., 49 pp., Cont.-in-part of U.S. Ser. No. 630,446. CODEN: USXXCO |
| LANGUAGE:
| English |
PATENT INFORMATION: PATENT NO. KIND DATE APPLICATION NO. DATE
--------------- ---- -------- -------------------- --------
US 2006024365 A1 20060202 US 2005-134633 20050519
IN 2002MU00697 A 20040529 IN 2002-MU697 20020805
IN 193042 A1 20040626
IN 2002MU00699 A 20040529 IN 2002-MU699 20020805
IN 2003MU00080 A 20050204 IN 2003-MU80 20030122
IN 2003MU00082 A 20050204 IN 2003-MU82 20030122
US 2004096499 A1 20040520 US 2003-630446 20030729
ABSTRACT:
A dosage form comprising of a high dose, high soly. active ingredient as modified release and a low dose active ingredient as immediate release where the wt. ratio of immediate release active ingredient and modified release active ingredient is from 1:10 to 1:15000 and the wt. of modified release active ingredient per unit is from 500 mg to 1500 mg; a process for prepg. the dosage form. Tablets contg. 10 mg sodium pravastatin and 1000 mg niacin were prepd. The release of sodium pravastatin after 24 h was 67.7%, and the release of niacin after 1 h was 84.1%.
Updated 1/25/2008 1:06:07 PM
