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CAPLUS COPYRIGHT 2007 ACS on STN
| TITLE:
| Dosage form containing modified- and immediated-release portions |
| INVENTOR(S):
| Vaya, Navin; Karan, Rajesh Singh; Nadkarni, Sunil Sadanand |
| PATENT ASSIGNEE(S):
| Torrent Pharmaceuticals Limited, India; Guota Vinod, Kumar |
| SOURCE:
| PCT Int. Appl., 65 pp. CODEN: PIXXD2 |
| LANGUAGE:
| English |
PATENT INFORMATION: PATENT NO. KIND DATE APPLICATION NO. DATE
--------------- ---- -------- -------------------- --------
WO 2004012700 A2 20040212 WO 2003-IN262 20030801
WO 2004012700 A3 20040401
W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN,
CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH,
GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR,
LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM,
PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN,
TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
RW: GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW, AM, AZ, BY,
KG, KZ, MD, RU, TJ, TM, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES,
FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR,
BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG
IN 193042 A1 20040626 IN 2002-MU697 20020805
AU 2003274681 A1 20040223 AU 2003-274681 20030801
EP 1528917 A2 20050511 EP 2003-758649 20030801
R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE, MC, PT,
IE, SI, LT, LV, FI, RO, MK, CY, AL, TR, BG, CZ, EE, HU, SK
BR 2003013424 A 20050614 BR 2003-13424 20030801
US 2006153916 A1 20060713 US 2006-522989 20060201
ABSTRACT:
A dosage form comprising of a high dose, high soly. active ingredient as modified release and a low dose active ingredient as immediate release where the wt. ratio of immediate release active ingredient and modified release active ingredient is from 1:10 to 1:15000 and the wt. of modified release active ingredient per unit is from 500 mg to 1500 mg; a process for prepg. the dosage form. An inner portion contained pravastatin sodium, lactose monohydrate, starch, Mg stearate, Na starch glycolate and dye to make tablets. An outer portion contained niacin, Eudragit RSPO to form granules and they were coated with hydrogenated castor oil in acetone and mixed with Mg stearate. Tablets were prepd. by compression such that the resultant tablets have an inner portion covered by the outer portion from all sides except the top surface that remains uncovered and the level of the inner portion and the outer portion is on the same surface.
Updated 4/24/2007 1:17:44 PM
