Following is one of the patent documents most requested by researchers using CAS electronic products.
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CAS indexed 63 chemical substances from this document.
CAS subject entries for this document include: Infection; Gastrointestinal motility; Heart, disease; and 26 additional concepts. | |
CAPLUS COPYRIGHT 2005 ACS on STN
| TITLE:
| Preparation of biphenyloxazolidinones and related compounds for treatment of infection, proliferative disease, inflammation, and gastrointestinal mobility disorders. |
| INVENTOR(S):
| Oyelere, Adegboyega K.; Goldberg, Joel A.; Orbin, Alia; Salvino, Joseph M.; Zhou, Jiacheng |
| PATENT ASSIGNEE(S):
| Rib-X Pharmaceuticals, Inc., USA |
| SOURCE:
| PCT Int. Appl., 78 pp. CODEN: PIXXD2 |
| LANGUAGE:
| English |
PATENT INFORMATION: PATENT NO. KIND DATE APPLICATION NO. DATE
--------------- ---- -------- -------------------- --------
WO 2005012270 A2 20050210 WO 2004-US24334 20040728
W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH,
CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD,
GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC,
LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI,
NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY,
TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
RW: BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW, AM,
AZ, BY, KG, KZ, MD, RU, TJ, TM, AT, BE, BG, CH, CY, CZ, DE, DK,
EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE,
SI, SK, TR, BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE,
SN, TD, TG
US 2005203147 A1 20050915 US 2005-118808 20050429
ABSTRACT:
MXLA(R1)mB(R2)nQ [A, B = Ph, pyridyl, pyrazinyl, pyrimidinyl, pyridazinyl; Q = Q1-Q4; M = Q5L1C(:W)L2; L1, L2 = bond, (R4-substituted) alkyl; Q5 = H, N(R4)2, OR4, (R4-substituted) alkyl; W = O, S; X = NR4, NR4NR4, S; L = (R4-substituted) alkyl; R1, R2 = F, Cl, Br, iodo, CF3, cyano, NO2, OR7, N(R7)2, COR7, CO2R7, CON(R7)2, etc.; R3 = OR7, N(R7)2, COR7, CO2R7, CON(R7)2, etc.; R4 = H, :O, :S, NR5, NOR5, :NN(R5)2, OR5, NO2, N(R5)2, etc.; R5 = H, (substituted) alkyl, alkylcarbonyl, alkoxycarbonyl; R6 = OH, alkoxy, SH, NO2, NH2, etc.; R7 = H, (substituted) alkyl, alkenyl alkynyl, (unsatd.) carbocyclyl, heterocyclyl, etc.; m, n = 0-4], were prepd. as drugs (no data). Thus, title compd. (I) was prepd. in several steps from N-[3-(3-fluoro-4-iodophenyl)-2-oxooxazolidin-5-ylmethyl]acetamide, 4-hydroxymethylphenylboronic acid, and bromoacetamide.
Updated 5/10/2007 1:11:22 PM
