Following is one of the patent documents most requested by researchers using CAS electronic products.
|
CAS indexed 29 chemical substances from this document.
CAS subject entries for this document include: Anti-inflammatory agents; Conformation; Nutrients; and 7 additional concepts. | |
CAPLUS COPYRIGHT 2004 ACS on STN
| TITLE:
| Use of protein conformation for the protection and release of chemical compounds |
| INVENTOR(S):
| Latham, Keith R. |
| PATENT ASSIGNEE(S):
| Innovative Technologies, LLC, USA |
| SOURCE:
| PCT Int. Appl., 27 pp. CODEN: PIXXD2 |
| LANGUAGE:
| English |
PATENT INFORMATION: PATENT NO. KIND DATE APPLICATION NO. DATE
--------------- ---- -------- --------------- --------
WO 2000052078 A1 20000908 WO 2000-US5693 20000306
W: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU,
CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL,
IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA,
MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI,
SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW, AM,
AZ, BY, KG, KZ, MD, RU, TJ, TM
RW: GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW, AT, BE, CH, CY, DE,
DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, BF, BJ, CF,
CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG
EP 1257592 A1 20021120 EP 2000-916076 20000306
R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE, MC, PT,
IE, SI, LT, LV, FI, RO, MK, CY, AL
US 2002128177 A1 20020912 US 2001-986426 20011108
US 2004063628 A1 20040401 US 2002-156527 20020529
ABSTRACT:
Disclosed are methods of combining chem. compds. with synthetic amino acid polymers for protection from degrdn. and to provide for controlled release of the compds. A method is described for the selective release of drug substances from a synthetic amino acid polymer in the stomach or small intestine, utilizing pH-dependent changes in higher order structure. A pharmaceutical compn. comprising a drug substance that has been combined with an amino acid polymer and a pharmaceutically acceptable combination of excipients is disclosed. Thus, polymeric glutamic acid (PGlu), polymeric lysine (PLys), and glutamic acid/phenylalanine copolymers were synthesized from the N-carboxyanhydrides. The release of tryptophan from PGlu + Trp or PLys + Trp blended tablets is discussed.
Updated 5/8/2007 10:28:27 AM
