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Most Requested Journal Articles 2Q02-Chemistry and Related
Following is one of the documents most requested by researchers using CAS electronic products.
CAPLUS COPYRIGHT 2002 ACS
The Pd-catalyzed cross-coupling reaction between organoboron compds. and org. halides or triflates provides a powerful and general methodol. for the formation of C-C bonds. Recently, this reaction was called the Suzuki coupling, Suzuki reaction, or Suzuki-Miyaura coupling, although the authors never referred to it as such previously. In this review, this name will be used with hesitation, simply to express the coupling reaction. The availability of the reagents and the mild reaction conditions all contribute to the versatility of this reaction. The coupling reaction offers several addnl. advantages, such as being largely unaffected by the presence of H2O, tolerating a broad range of functional groups, and proceeding generally regio- and stereoselectively. Also, the inorg. byproduct of the reaction is nontoxic and easily removed from the reaction mixt. thereby making the Suzuki coupling suitable not only for labs. but also for industrial processes. The authors published previously a comprehensive review of the reaction which covered mainly the refs. until the end of 1994. Thereafter, a large no. of papers related to the coupling reaction are reported. Consequently, such new results presented from 1995 to May 1998 are summarized in this review, with 139 refs. View full-text pdf document from the Elsevier Science, a participating ChemPort publisher. Updated 5/7/2007 10:59:37 AM
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