Following is one of the journal articles most requested by researchers using CAS online services.
|
CAS indexed 45 chemical substances from this document.
CAS subject entries for this document include: Coupling reaction; Aromatic hydrocarbons, preparation; Aryl halides; and 2 additional concepts. | |
CAPLUS COPYRIGHT 2004 ACS on STN
| TITLE:
| Efficient palladium-catalyzed coupling of aryl chlorides and tosylates with terminal alkynes: Use of a copper cocatalyst inhibits the reaction |
| AUTHOR(S):
| Gelman, Dmitri; Buchwald, Stephen L. |
| CORPORATE SOURCE:
| Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA |
| SOURCE:
| Angewandte Chemie, International Edition (2003), 42(48), 5993-5996 CODEN: ACIEF5; ISSN: 1433-7851 |
| PUBLISHER:
| Wiley-VCH Verlag GmbH & Co. KGaA |
| LANGUAGE:
| English |
ABSTRACT:A general method for the palladium-catalyzed coupling of terminal alkynes with aryl halides and tosylates is described. The coupling reaction was investigated with copper as a cocatalyst, but better results were obtained in the absence of the cocatalyst, which inhibited the product formation.
Updated 5/3/2007 3:31:10 PM
