Following is a CAS database record representing a highly cited patent family.
|
CAS indexed 32 chemical substances from this document.
CAS subject entries for this document include: Bactericides, Disinfectants, and Antiseptics. | |
CAPLUS COPYRIGHT 2006 ACS on STN
| TITLE:
| Fluoromethylthiooxacephalosporins |
| INVENTOR(S):
| Tsuji, T.; Sato, H.; Hamashima, Y. |
| PATENT ASSIGNEE(S):
| Shionogi and Co., Ltd. , Japan |
| SOURCE:
| Belg., 47 pp. CODEN: BEXXAL |
| LANGUAGE:
| French |
PATENT INFORMATION: PATENT NO. KIND DATE APPLICATION NO. DATE
--------------- ---- -------- -------------------- --------
BE 898541 A1 19840416 BE 1983-212107 19831222
JP 59139385 A2 19840810 JP 1982-234472 19821223
JP 62025671 B4 19870604
ES 527595 A1 19850616 ES 1983-527595 19831128
ZA 8308920 A 19840725 ZA 1983-8920 19831130
AU 8322113 A1 19840628 AU 1983-22113 19831206
AU 558547 B2 19870205
GB 2132198 A1 19840704 GB 1983-33186 19831213
GB 2132198 B2 19861001
FR 2538391 A1 19840629 FR 1983-20221 19831216
FR 2538391 B1 19861219
FI 8304682 A 19840624 FI 1983-4682 19831219
FI 74016 B 19870831
FI 74016 C 19871210
DE 3345989 A1 19840628 DE 1983-3345989 19831220
DE 3345989 C2 19920924
IL 70488 A1 19880331 IL 1983-70488 19831220
CA 1236099 A1 19880503 CA 1983-443807 19831220
DK 8305895 A 19840624 DK 1983-5895 19831221
DK 159447 B 19901015
DK 159447 C 19910408
SE 8307079 A 19840624 SE 1983-7079 19831221
SE 461527 B 19900226
SE 461527 C 19900621
NO 8304729 A 19840625 NO 1983-4729 19831221
NO 167740 B 19910826
NO 167740 C 19911204
AT 8304468 A 19870115 AT 1983-4468 19831221
AT 383807 B 19870825
NL 8304409 A 19840716 NL 1983-4409 19831222
NL 192740 B 19970901
NL 192740 C 19980106
HU 34200 O 19850228 HU 1983-4424 19831222
HU 189014 B 19860630
US 4532233 A 19850730 US 1983-564553 19831222
CH 656619 A 19860715 CH 1983-6917 19831223
ES 534288 A1 19850601 ES 1984-534288 19840713
ES 534289 A1 19850601 ES 1984-534289 19840713
ES 534290 A1 19850601 ES 1984-534290 19840713
ES 534291 A1 19870216 ES 1984-534291 19840713
ES 556846 A1 19871001 ES 1986-556846 19860701
AT 8602564 A 19890615 AT 1986-2564 19860925
AT 389699 B 19900110
CA 1259989 A2 19890926 CA 1987-554185 19871211
SE 8802008 A 19880530 SE 1988-2008 19880530
SE 470132 B 19931115
SE 470132 C 19940310
ABSTRACT:
Cephalosporins I [R = H, F; R1 = H, cation, protective group; R2 = (un)protected 2-hydroxyalkyl] were prepd. Thus, II was acylated with F2CHSCH2COCl and treated with Na 1-(2-hydroxyethyl)tetrazole-5-thiolate to give I (R = F, R1 = CHPh2, R2 = CH2CH2OH) which was hydrolyzed to the acid and treated with NaHCO3 to give I (R = F, R1 = Na, R2= CH2CH2OH). The salt had a min. inhibitory concn. against Escherichia coli of <0.1 .mu.g/mL.
Updated 5/3/2007 2:20:09 PM
