Following is a CAS database record representing a highly cited patent family.
|
CAS indexed 142 chemical substances from this document.
CAS subject entries for this document include: Prostaglandins. | |
CAPLUS COPYRIGHT 2005 ACS on STN
| TITLE:
| 9-Fluoroprostaglandin derivatives and their use as pharmaceuticals |
| INVENTOR(S):
| Skuballa, Werner; Raduechel, Bernd; Schwarz, Norbert; Vorbrueggen, Helmut; Elger, Walter; Loge, Olaf; Town, Michael Harold |
| PATENT ASSIGNEE(S):
| Schering A.-G. , Fed. Rep. Ger. |
| SOURCE:
| Ger. Offen., 42 pp. CODEN: GWXXBX |
| LANGUAGE:
| German |
PATENT INFORMATION: PATENT NO. KIND DATE APPLICATION NO. DATE
--------------- ---- -------- -------------------- --------
DE 3126924 A1 19830120 DE 1981-3126924 19810703
CA 1218060 A1 19870217 CA 1982-405837 19820623
JP 58008059 A2 19830118 JP 1982-107696 19820624
JP 04043906 B4 19920720
SU 1301308 A3 19870330 SU 1982-3456800 19820624
EP 69696 A2 19830112 EP 1982-730087 19820625
EP 69696 A3 19830316
EP 69696 B1 19860115
R: AT, BE, CH, DE, FR, GB, IT, LI, LU, NL, SE
AT 17475 E 19860215 AT 1982-730087 19820625
CS 236484 B2 19850515 CS 1982-4906 19820629
IL 66165 A1 19860131 IL 1982-66165 19820629
DK 8202943 A 19830104 DK 1982-2943 19820630
DK 154073 B 19881010
DK 154073 C 19890227
AU 8285528 A1 19830106 AU 1982-85528 19820701
AU 559449 B2 19870312
ES 513645 A1 19830316 ES 1982-513645 19820701
HU 27410 O 19831028 HU 1982-2185 19820702
HU 190692 B 19861028
US 4454339 A 19840612 US 1982-395448 19820706
US 4789685 A 19881206 US 1987-4733 19870120
DK 8701235 A 19870310 DK 1987-1235 19870310
ABSTRACT:
I [A = CH2CH2 or cis-CH:CH; R = CH2OH or CO2H or a deriv.; Q = CH2CH2, trans-CH:CH, C.tplbond.C; X = CH(OH) or deriv.; YZ = bond or Y = C1-10 (fluoro) alkylene, Z = O, S, alkylene, etc.; R1 = OH or deriv.; R2 = alkyl, cycloalkyl, aryl, etc.] were prepd. from known prostaglandin derivs. Thus, Me (5Z,9S,11R,13E,15R)-9-hydroxy-16-phenoxy-11,15-bis[(tetrahydropyranyl)oxy]-1 7,18,19,20-tetranor-5,13-prostadienoate was tosylated, treated with Bu4NF, and deprotected to give II.
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Updated 5/3/2007 12:51:03 PM
