Following is a CAS database record representing a highly cited patent family.
|
CAS indexed 27 chemical substances from this document.
CAS subject entries for this document include: Drug bioavailability; Pharmaceuticals; Castor oil; and 4 additional concepts. | |
CAPLUS COPYRIGHT 2003 ACS
| TITLE:
| Pharmaceutical preparation containing a poorly soluble drug with improved bioavailability |
| INVENTOR(S):
| Posanski, Ulrich |
| PATENT ASSIGNEE(S):
| Galenik Labor Freiburg GmbH, Germany |
| SOURCE:
| Ger. Offen., 5 pp. CODEN: GWXXBX |
| LANGUAGE:
| German |
PATENT INFORMATION: PATENT NO. KIND DATE APPLICATION NO. DATE
--------------- ---- -------- --------------- --------
DE 4322826 A1 19950112 DE 1993-4322826 19930708
CA 2164100 AA 19950119 CA 1994-2164100 19940708
WO 9501785 A1 19950119 WO 1994-EP2238 19940708
W: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, ES, FI, GB,
GE, HU, JP, KE, KG, KP, KR, KZ, LK, LT, LU, LV, MD, MG, MN, MW,
NL, NO, NZ, PL, PT, RO, RU, SD, SE, SI, SK, TJ, TT, UA, US, UZ, VN
RW: KE, MW, SD, AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC,
NL, PT, SE, BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG
WO 9501786 A1 19950119 WO 1994-EP2248 19940708
W: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, ES, FI, GB,
GE, HU, JP, KE, KG, KP, KR, KZ, LK, LT, LU, LV, MD, MG, MN, MW,
NL, NO, NZ, PL, PT, RO, RU, SD, SE, SI, SK, TJ, TT, UA, US, UZ, VN
RW: KE, MW, SD, AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC,
NL, PT, SE, BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG
AU 9473457 A1 19950206 AU 1994-73457 19940708
AU 689486 B2 19980402
AU 9473850 A1 19950206 AU 1994-73850 19940708
EP 710103 A1 19960508 EP 1994-922269 19940708
EP 710103 B1 20010613
R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE
EP 710104 A1 19960508 EP 1994-923715 19940708
EP 710104 B1 19981104
R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE
HU 73427 A2 19960729 HU 1995-3868 19940708
CN 1128495 A 19960807 CN 1994-192714 19940708
BR 9407002 A 19960903 BR 1994-7002 19940708
HU 73661 A2 19960930 HU 1995-3965 19940708
JP 08512301 T2 19961224 JP 1994-503830 19940708
JP 08512303 T2 19961224 JP 1994-503833 19940708
AT 172876 E 19981115 AT 1994-923715 19940708
ES 2124420 T3 19990201 ES 1994-923715 19940708
RU 2140291 C1 19991027 RU 1996-102012 19940708
SK 280615 B6 20000516 SK 1996-19 19940708
PL 179717 B1 20001031 PL 1994-312255 19940708
EP 1092429 A1 20010418 EP 2000-122248 19940708
R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE, PT, IE, SI
ES 2159564 T3 20011016 ES 1994-922269 19940708
CZ 291401 B6 20030312 CZ 1996-45 19940708
FI 9600032 A 19960209 FI 1996-32 19960103
FI 9600042 A 19960104 FI 1996-42 19960104
NO 9600062 A 19960105 NO 1996-62 19960105
NO 9600069 A 19960105 NO 1996-69 19960105
US 2002099067 A1 20020725 US 2002-40842 20020107
ABSTRACT:
The title prepn. contains a poorly sol. drug and a carrier comprising (a) .gtoreq.1 fatty ester of polyglycerol or sorbitan as cosurfactant, (b) .gtoreq.1 triglyceride oil, and (c) .gtoreq.1 nonionic surfactant with HLB .gtoreq.10. Thus, a soln. was prepd. by heating cyclosporin A 100.0, ethoxylated castor oil 400.0, di/tri/tetraglycerol fatty ester 240.0, sesame oil 160.0, and EtOH 100.0 mg to 40.degree. and dispensed into soft gelatin capsules.
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