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Most Cited Journal Articles 2005-Medical Sciences

The following records identify the top ten, most cited journal articles appearing in documents published in 2005.

Title	Author/Affiliation	Source
1. The hallmarks of cancer [details]	Hanahan, Douglas; Weinberg, Robert A. Department of Biochemistry and Biophysics and Hormone Research Institute, University of California at San Francisco, San Francisco, CA, 94143, USA	Cell (Cambridge, Mass.)
2. Dendritic cells and the control of immunity [details]	Banchereau, Jacques; Steinman, Ralph M. Baylor Inst. for Immunol., Res., Baylor Res. Inst., Dallas, TX, 75246, USA	Nature (London)
3. Homeostasis model assessment: insulin resistance and .beta.-cell function from fasting plasma glucose and insulin concentrations in man [details]	Matthews, D. R.; Hosker, J. P.; et al. Diabetes Res. Lab., Radcliffe Infirm., Oxford, OX2 6HE, UK	Diabetologia
4. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib [details]	Lynch, Thomas J.; Bell, Daphne W.; et al. Cancer Center and Departments of Medicine and Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA	N. Engl. J. Med.
5. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy [details]	Paez, J. Guillermo; Jaenne, Pasi A.; et al. Departments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA	Science (Washington, DC, U. S.)
6. Nitric oxide: physiology, pathophysiology, and pharmacology [details]	Moncada, S.; Palmer, R. M. J.; et al. Wellcome Res. Lab., Beckenham/Kent, UK	Pharmacol. Rev.
7. Toll-like receptors [details]	Takeda, Kiyoshi; Kaisho, Tsuneyasu; et al. Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, 565-0871, Japan	Annu. Rev. Immunol.
8. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene [details]	Poltorak, Alexander; He, Xiaolong; et al. Howard Hughes Med. Inst. and the Dep. of Internal Medicine, Univ. Texas Southwestern Med. Cent., Dallas, TX, 75235-9050, USA	Science (Washington, D. C.)
9. Positional cloning of the mouse obese gene and its human homolog [details]	Zhang, Yiying; Proenca, Richardo; et al. Howard Hughes Med. Inst., Rockefeller Univ., New York, NY, 10021, USA	Nature (London)
10. Immunobiology of dendritic cells [details]	Banchereau, Jacques; Briere, Francine; et al. Baylor Institute for Immunology Research, Dallas, TX, 75204, USA	Annu. Rev. Immunol.