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Most Cited Journal Articles 2002-Medical Sciences

Following is a CAS database record representing a highly cited journal article.

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CAS subject entries for this document include: Leukocyte; Signal transduction, biological; Circulation; and 3 additional concepts.

CAPLUS COPYRIGHT 2003 ACS

TITLE:	Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
AUTHOR(S):	Springer, Timothy A.
CORPORATE SOURCE:	Cent. Blood Res., Harvard Med. Sch., Boston, MA, 02115, USA
SOURCE:	Cell (Cambridge, MA, United States) (1994), 76(2), 301-14 CODEN: CELLB5; ISSN: 0092-8674
PUBLISHER:	Cell Press
LANGUAGE:	English

ABSTRACT:
A review, with 104 refs., on the traffic signals that enable selective emigratory behavior of monocytes and neutrophils and an elaboration on how the same paradigm can be extended to lymphocyte recirculation. Many aspects of the paradigm, esp. the interplay between integrins and chemoattractants, may be relevant to other systems, such as the migration of individual cells in development and tissue repair.