Following is a CAS database record representing a highly cited journal article.
CAS indexed 1 chemical substance from this document.
CAS subject entries for this document include: Coliphage T4; Polyacrylamide gel electrophoresis; Proteins, specific or class. | |
CAPLUS COPYRIGHT 2001 ACS
| TITLE: |
Cleavage of structural proteins during the assembly of the head of bacteriophage T4 |
| AUTHOR(S): |
Laemmli, U. K. |
| CORPORATE SOURCE: |
MRC Laboratory of Molecular Biology, Cambridge, UK |
| SOURCE: |
Nature (London, U. K.) (1970), 227(5259), 680-685 CODEN: NATUAS; ISSN: 0028-0836 |
| PUBLISHER: |
Nature Publishing Group |
| LANGUAGE: |
English |
ABSTRACT:
Using an improved method of polyacrylamide gel electrophoresis based on the capability of SDS to break down proteins into their individual polypeptide chains, many previously unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products. Four major components of the head are cleaved during the process of assembly, apparently after the precursor proteins have assembled into some large intermediate structure.
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Updated 7/31/2007 8:27:38 AM
