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Most Cited Journal Articles 2000-Chemistry

 

Following is a CAS database record representing a highly cited journal article.

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CAS indexed 4 chemical substances from this document. CAS subject entries for this document include: Computer program; Proteins; Bacteriorhodopsins; and 8 additional concepts.

CAPLUS COPYRIGHT 2002 ACS

TITLE:	A simple method for displaying the hydropathic character of a protein
AUTHOR(S):	Kyte, Jack; Doolittle, Russell F.
CORPORATE SOURCE:	Dep. Chem., Univ. California, La Jolla, CA, 92093, USA
SOURCE:	J. Mol. Biol. (1982), 157(1), 105-32 CODEN: JMOBAK; ISSN: 0022-2836
PUBLISHER:	Academic Press
LANGUAGE:	English

ABSTRACT:
A computer program that progressively evaluates the hydrophilicity and hydrophobicity of a protein along its amino acid sequence was devised. A hydropathy scale takes into consideration the hydrophilic and hydrophobic properties of each of the 20 amino acid side chains. Correlation was demonstrated between the plotted values and known structures detd. by crystallog.