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CAPLUS COPYRIGHT 2012 ACS
|Patent Number: ||US 8273897 |
|Title: ||Preparation of 2,2-difluoroethylamines via amide hydrogenation |
|Inventor(s): ||Lui, Norbert; Antons, Stefan |
|Patent Assignee(s): ||Bayer CropScience A.-G., Germany |
|Source: ||PCT Int. Appl., 24 pp. CODEN: PIXXD2 |
|Language: ||German |
A process for the preparation of title compds. I [A = pyrid-2-yl, pyrid-4-yl, etc.] via the hydrogenation of amides II was disclosed. For example, NaBH4/BF3 mediated reduction of amide III [X = O] afforded difluoroethylamine III [X = H] in 95% yield.
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Note: Abstracts for patent records in CAplus are routinely enhanced to better describe the claimed invention. CAS enhanced the abstract using additional information found in the patent.