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CAPLUS COPYRIGHT 2011 ACS
||Synthesis of galantamine and intermediates
||Wang, Lunghu; Chen, Yung Fa; Henschke, Julian Paul
||ScinoPharm Taiwan Ltd., Taiwan
||U.S. Pat. Appl. Publ., 9pp. CODEN: USXXCO
A novel process for the preparation of N-methyl-N-(2-[4-hydroxyphenyl]ethyl)-5- hydroxy-4-methoxybenzenecarboxamide, which is useful as an intermediate in the synthesis of (-)-galantamine, comprises the reaction of a 5-hydroxy-4-methoxybenzoic acid derivative with N-methyl-N-(2-[4-hydroxyphenyl]ethyl)amine.
Please note: The titles for patent records in CAplus are routinely enhanced to better describe the claimed invention. In this example, the original title of the U.S. granted patent is Process for making galantamine. For the CAplus record, this title was enhanced to read Synthesis of galantamine and intermediates.
View the full-text U.S. patent from USPTO.