August 27, 2012

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 63 patent authorities around the world, and other reputable web sources.

The following patent record is from the CAplusSM database.

CAPLUS COPYRIGHT 2012 ACS

Patent Number: US 8232392
Title: Process for preparation of temozolomide
Inventor(s): Turchetta, Stefano; De Ferra, Lorenzo; Zenoni, Maurizio; Anibaldi, Mauro
Patent Assignee(s): Chemi SpA, Italy
Source: Eur. Pat. Appl., 9pp. CODEN: EPXXDW
Language: English

Abstract:
This invention provides a process for the preparation of temozolomide. For example, 5-aminoimidazole-4-carboxamide was reacted with N-succinimidyl-N'-Me carbamate in the presence of diisopropylethylamine to obtain 5-amino-N1-Me-imidazole-1,4-dicarboxamide, followed by cyclization with a nitrite, chromatog. purification, and crystallization to give the title compound.

Please note:  Titles and abstracts for patent records in CAplus are routinely enhanced to better describe the claimed invention.

 

View the full-text U.S. patent from USPTO.

Recent News

    
    August 21, 2016 | CAS announces SciFindern, a new
    research experience that elevates scientific discovery

    August 19, 2016 | CAS seeks to help undergraduate
    students think like researchers with Chemistry
    Class Advantage, an organic chemistry learning
    solution powered by SciFinder

    August 1, 2016 | CAS Strengthens its Commitment to
    Science and Innovation Selecting 26 Outstanding
    International Scientists to Participate in the 2016
    SciFinder Future Leaders Program

 
                                                                    More News >> 
 
 

Media Contact

 Name: Rhonda Ross
 Phone: 614-447-3624
 Email: cas-pr@cas.org