August 27, 2012

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 63 patent authorities around the world, and other reputable web sources.

The following patent record is from the CAplusSM database.

CAPLUS COPYRIGHT 2012 ACS

Patent Number: US 8232392
Title: Process for preparation of temozolomide
Inventor(s): Turchetta, Stefano; De Ferra, Lorenzo; Zenoni, Maurizio; Anibaldi, Mauro
Patent Assignee(s): Chemi SpA, Italy
Source: Eur. Pat. Appl., 9pp. CODEN: EPXXDW
Language: English

Abstract:
This invention provides a process for the preparation of temozolomide. For example, 5-aminoimidazole-4-carboxamide was reacted with N-succinimidyl-N'-Me carbamate in the presence of diisopropylethylamine to obtain 5-amino-N1-Me-imidazole-1,4-dicarboxamide, followed by cyclization with a nitrite, chromatog. purification, and crystallization to give the title compound.

Please note:  Titles and abstracts for patent records in CAplus are routinely enhanced to better describe the claimed invention.

 

View the full-text U.S. patent from USPTO.

Recent News

 
    April 17, 2014 | Multi-Year Deal Secures SciFinder
    Access for Prague Consortium Researchers

    April 16, 2014 | New Format Adopted for Taiwanese
    Granted Patent Numbers in CAS Databases and
    INPADOC

    March 26, 2014 | New STN Platform Enhancements
    Available, Increase Efficiency of Search Workflow

                                                                       More News >> 

 Media Contact

 Name: Rhonda Ross
 Phone: 614-447-3624                                       
 Email: cas-pr@cas.org