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Patent Watch--August 10, 2009

The following record is from the CAplus^SM database

CAPLUS COPYRIGHT 2009 ACS

PATENT NUMBER:	US 7538232
TITLE:	Improved process for the asymmetric synthesis of duloxetine
INVENTOR(S):	Butchko, Mark Anthony; Merschaert, Alain; Moder, Kenneth Philip
PATENT ASSIGNEE(S):	Eli Lilly and Company, USA
SOURCE:	U. S. Pat. Appl. Publ., 6 pp. CODEN: USXXCO
LANGUAGE:	English

ABSTRACT: This invention provides an improved asym. process for the synthesis of duloxetine (I) involving arylation of compds. of formula II, wherein R is H and Me. Compd. I was prepd. by arylation of II (R = H) with 1-fluoronaphthalene.

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