June 9, 2014

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 63 patent authorities around the world, and other reputable web sources.

The following patent record is from the CAplusSM database.

CAPLUS COPYRIGHT 2014 ACS

Patent Number: WO 2014055474
Title: Preparation of mannose derivatives for treating bacterial infections
Inventor(s): Bennani, Youssef Laafiret; Liu, Bingcan
Patent Assignee(s): Vertex Pharmaceuticals Incorporated, USA
Source: PCT Int. Appl., 81pp. CODEN: PIXXD2
Language: English

Abstract:
Disaccharides I, wherein ring A is a substituted sugar residue; each X is independently substituted amine, O, S; Y and Z are independently substituted amine, O, S; R' is absent, H, halogen, substituted O, substituted N, substituted S, alkyl, alkenyl, alkynyl, cycloalkyl; R is H, halogen, substituted O, substituted N, substituted S, alkyl, alkenyl, alkynyl, cycloalkyl; R and R' together form a cyclic ring or heterocyclic ring; R1 is alkyl, allkenyl, alkynyl, cycloalkyl, heterocyclyl, heteroaryl, were prepd. and used for the treatment or prevention of bacteria infections.  Thus, disaccharide II was prepd. and tested in vitro as antibacterial agent (Kd = 0.029 µM).

Please note:  Abstracts and Titles for patent records in CAplus are routinely enhanced to better describe the claimed invention.

 

 View the full-text here.

Recent News


    December 22, 2016 | CAS announces highly 
    anticipated early access of its revolutionary new 
    solution, SciFindern to select organizations

    December 19, 2016 | CAS Convenes Executive
    Innovation Summits to Inspire Global Economic
    Growth

    August 21, 2016 | CAS announces SciFindern, a new
    research experience that elevates scientific discovery

                                                                    More News >> 

 Media Contact

 Name: Rhonda Ross
 Phone: 614-447-3624                                       
 Email: cas-pr@cas.org