April 15, 2013

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 63 patent authorities around the world, and other reputable web sources.

The following patent record is from the CAplusSM database.


Patent Number: US 8362006
Title: Processes for preparation of zilpaterol via chlorination of 4-(2-oxo-2,3-dihydrobenzimidazol-1-yl)butyric acid or nitrosation of 8,9-dihydro-2H,7H-2,9a-diazabenzo[cd]azulene-1,6-dione.
Inventor(s): Dubuis, Stephane; Krebs, Oliver
Patent Assignee(s): Intervet International B.V., Neth.
Source: PCT Int. Appl., 54pp. CODEN: PIXXD
Language: English

Processes for preparation of zilpaterol include chlorination of 4-(2-oxo-2,3-dihydrobenzimidazol-1-yl)butyric acid with oxalyl chloride, phosgene, or triphosgene to give the acid chloride and reaction of 8,9-dihydro-2H,7H-2,9a-diazabenzo[cd]azulene-1,6-dione with an inorg. nitrite to give 4,5-dihydroimidazo[4,5,1-jk][1]benzazepin-2,6,7[1H]-trione-6-oxime.

Please note:  Abstracts and Titles for patent records in CAplus are routinely enhanced to better describe the claimed invention. The title of the U.S. granted patent is Processes for making zilpaterol and salts thereof.

 View the full-text here.

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