February 21, 2011

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 61 patent authorities around the world, and other reputable web sources.

The following patent record is from the CAplusSM database.

CAPLUS COPYRIGHT 2011 ACS

Patent Number: US 7858821
Title: A process for preparing intermediate compounds useful for producing dolasetron
Inventor(s): Perez Andres, Juan Antonio; Dalmases Barjoan, Pere; Huguet Clotet, Joan
Patent Assignee(s): Inke, S.A., Spain
Source: U.S. Pat. Appl. Publ., 20pp. CODEN: USXXCO
Language: English
Abstract:
The invention relates to a process for the preparation of compds. I (wherein R1 is alkyl, R2 and R3 are independently alkyl, or both R2 and R3 attached resp. to the oxygen atoms belonging to the same carbon atom form a cycle), which are useful for producing dolasetron.  For instance, the compound I (R1 = R2 = R3 = Me) was prepared by substitution of di-Me malonate with bromoacetaldehyde di-Me acetal followed by dealkoxycarbonylation in 75% yield, which was converted to dolasetron in about 5 steps.

 

View the full-text patent from USPTO.

Recent News

    
    October 7, 2014 | CAS and Obiter Research form a
    multi-year collaboration to provide SciFinder to their
    research team
    
    September 29, 2014
| Cooperative Patent Classification
    (CPC) Combination Set Data Now Available in CAplus,
    INPADOCDB and USPAT Databases
         
    September 22, 2014
| STN Global Value Pricing
    Agreement Supports the Swedish Patent and
    Registration Office in Providing High Quality and
    Efficient Examination
    
 
                                                                     More News >> 

 Media Contact

 Name: Rhonda Ross
 Phone: 614-447-3624                                       
 Email: cas-pr@cas.org