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The following patent record is from the CAplusSM
CAPLUS COPYRIGHT 2013 ACS
|Patent Number: ||US 8299305 |
|Title: ||Process for the production of substituted hydroxymethyl phenols |
|Inventor(s): ||Ennis, Seth; Kennedy, Bryan |
|Patent Assignee(s): ||Schwarz Pharma Ltd., Ire |
|Source: ||PCT Int. Appl., 28pp. CODEN: PIXXD2 |
|Language: ||English |
The invention relates to a process for the production of hydroxymethyl phenols I [wherein R1 is H, or (alkyl|phenyl)carbonyl] or its salts thereof, which is known as the active metabolite of tolterodine, and its phenolic monoesters by an improved synthetic route via a so-called "Turbo Grignard" reaction.
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Note: Abstracts and Titles for patent records in CAplus are routinely enhanced to better describe the claimed invention. The original title of the PCT publication is Accelerated synthesis of substituted hydroxymethyl phenols.