January 28, 2013

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 63 patent authorities around the world, and other reputable web sources.  

The following patent record is from the CAplusSM database.

CAPLUS COPYRIGHT 2013 ACS

Patent Number: US 8299305
Title: Process for the production of substituted hydroxymethyl phenols
Inventor(s): Ennis, Seth; Kennedy, Bryan
Patent Assignee(s): Schwarz Pharma Ltd., Ire
Source: PCT Int. Appl., 28pp. CODEN: PIXXD2
Language: English

Abstract:

The invention relates to a process for the production of hydroxymethyl phenols I [wherein R1 is H, or (alkyl|phenyl)carbonyl] or its salts thereof, which is known as the active metabolite of tolterodine, and its phenolic monoesters by an improved synthetic route via a so-called "Turbo Grignard" reaction.

View the full-text patent here.

Note: Abstracts and Titles for patent records in CAplus are routinely enhanced to better describe the claimed invention. The original title of the PCT publication is Accelerated synthesis of substituted hydroxymethyl phenols.

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