January 23, 2012

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 62 patent authorities around the world, and other reputable web sources.

The following patent record is from the CAplusSM database.

CAPLUS COPYRIGHT 2011 ACS

Patent Number: US 8067617
Title: Preparation of indolinonecarboxylates.
Inventor(s): Merten, Joern; Renner, Svenja; Reichel, Carsten
Patent Assignee(s): Boehringer Ingelheim International G.m.b.H., Germany
Source: PCT Int. Appl., 29pp. CODEN: PIXXD2
Language: English

Abstract:

Title compds. [I; R1 = H, ClCH2CO; R2, R3 = H; R2R3 = :C(OMe)Ph; when R1 = H, then R2R3 = :C(OMe)Ph], were prepared  Thus, di-Me malonate was heated with Na tert-amylate and Me 4-chloro-3-nitrobenzoate (preparation given) in N-methylpyrrolidone to give 95.4% di-Me [4-(methoxycarbonyl)-2-nitrophenyl]propanedioate. This was hydrogenated in HOAc over Pd/C at 45 degrees followed by heating at 115 degrees to give 87.2% 6-methoxycarbonyl-2-oxindole.

Please note:  Titles and abstracts for patent records in CAplus are routinely enhanced to better describe the claimed invention. In this example, CAS enhanced the abstract using additional information found in the patent.

View the full-text U.S. patent from USPTO.

Recent News

       
    March 17, 2015 | New Content Provides Regulatory
    Professionals with Additional Value
    
    February 9, 2015 | Major New STN Release Delivers
    Essential Biomedical and Patent Content to IP
    Professionals
    
    January 26, 2015
 | Annual MEDLINE Reload on STN
    Features Enhanced Clinical Trial Information and the
    2015 MeSH Thesaurus
                               
  
                                                                     More News >> 

 Media Contact

 Name: Rhonda Ross
 Phone: 614-447-3624                                       
 Email: cas-pr@cas.org