January 20, 2014

CAS databases provide millions of journal article references from more than 10,000 major scientific journals worldwide, patent and patent family references from 63 patent authorities around the world, and other reputable web sources.

The following patent record is from the CAplusSM database.


Patent Number: WO 2013176970
Title: Trka kinase inhibitors, compositions and methods thereof
Inventor(s): Stachel, Shawn J.; Egbertson, Melissa; Brnardic, Edward; Jones, Kristen; Sanders, John M.; Henze, Darrell A.
Patent Assignee(s): Merck Sharp & Dohme Corp., USA
Source: PCT Int. Appl., 77pp. CODEN: PIXXD2
Language: English

The present invention is directed to benzyl urea compds., which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence may be useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder assocd. with abnormal activities of nerve growth factor (NGF) receptor Trk-A, Trk-B and/or Trk-C.

Please note:  Abstracts and Titles for patent records in CAplus are routinely enhanced to better describe the claimed invention.

 View the full-text here.

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