The following record is from the CAplusSM database
CAPLUS COPYRIGHT 2009 ACS
| PATENT NUMBER: |
US 7442826 |
| TITLE: |
Esterification process for the preparation of nitrooxy derivatives of paracetamol |
| INVENTOR(S): |
Rivolta, Romano; Aureli, Roberto |
| PATENT ASSIGNEE(S): |
Nicox S. A., Fr. |
| SOURCE: |
PCT Int. Appl., 11 pp. CODEN: PIXXD2 |
| LANGUAGE: |
English |
ABSTRACT:
Nitrooxy derivs. of paracetamol 4-(AcNH)C6H4O2CXONO2 [X = (un)branched C1-20 alkylene; e.g., 4-(acetylamino)phenyl 4-(nitrooxy)butanoate] are prepd. by the esterification of 4-(acetylamino)phenolates 4-(AcNH)C6H4OM [M = H, Group IA or IIA cation, onium cation; e.g., 4-(acetylamino)phenol] with a nitrooxycarboxylic acid deriv. O2NOXCOY [Y = OH, Cl, OCO2R, O2CXCOY; R = alkyl; e.g., 4-(nitrooxy)butanoyl chloride]. |
| View the full-text patent from USPTO. |
Updated: 1/7/2009 7:39:59 AM
