Media Releases

CAS Registers 70 Millionth Substance Just 18 Months After Reaching 60 Millionth Milestone

December  6th,   2012

Patents from Asian countries continue to be the leading source of chemistry disclosures

Columbus, Ohio (December 6, 2012) – Chemical Abstracts Service (CAS), the world’s authority for chemical information, announced today a major milestone for the CAS REGISTRYSM, the largest collection of publicly disclosed chemical substance information. CAS scientists registered the 70 millionth substance from a patent application submitted to the Korean Intellectual Property Office (KIPO).

The 70 millionth substance is a potential T-type calcium channel blocker discovered at the Korea Institute of Science and Technology (KIST), a multidisciplinary research institute in Seoul, South Korea. Assigned CAS Registry Number® 1411769-41-9, the substance is one of several pyrazolyl-piperazine compounds disclosed in the patent application published by KIPO on November 14, 2012. This molecule may be useful in the treatment of epilepsy, Parkinson's disease, dementia and other conditions.

                                                         CAS Registry Number 1411769-41-9

N-[[5-(2-methylpropyl)-1-phenyl-1H-pyrazol-3-yl]methyl]- 4-[3-(trifluoromethyl)benzoyl]-
1-piperazineacetamide

“It’s exciting that this milestone was realized with a substance from a Korean patent considering our earlier reports that Asian scientists are disclosing more chemical research in patents,” said Christine McCue, vice president of marketing at CAS. “This year alone, 63 percent of all chemical patents covered by CAS originated in Asia. Our team of scientists analyzes documents in more than 50 languages, including more than 20 Asian languages, and is uniquely qualified to uncover important chemistry patented by scientists worldwide.”

Similar to the 60 millionth substance registered in May 2011, the 70 millionth substance again reflects the value of patents as an important source of chemical information. In fact, more than 70 percent of new substances from the literature registered in 2012 originated from patents. To ensure the completeness and quality of the CAS premier substance collection, CAS scientists analyze, organize and curate chemistry in patents from 63 patent authorities around the world, far more than any other service.


About CAS

Chemical Abstracts Service (CAS), a division of the American Chemical Society, is the world’s authority for chemical information. CAS is the only organization in the world whose objective is to find, collect and organize all publicly disclosed chemical substance information. A team of scientists worldwide curates and controls the quality of our databases, which are recognized as the most comprehensive and authoritative by chemical and pharmaceutical companies, universities, government organizations and patent offices around the world. By combining these databases with advanced search and analysis technologies (SciFinder® and STN®), CAS delivers the most current, complete, secure and interlinked digital information environment for scientific discovery.

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