2013 Nobel Prize-Winning Chemistry Research Documented in CAS Databases
On October 9, 2013, the Royal Swedish Academy of Sciences jointly awarded the Nobel Prize in Chemistry to three scientists “for the development of multiscale models for complex chemical systems.”
- Martin Karplus, Université de Strasbourg, France and Harvard University, Cambridge, MA, USA
- Michael Levitt, Stanford University School of Medicine, Stanford, CA, USA
- Arieh Warshel, University of Southern California, Los Angeles, CA, USA
Today's chemical modeling is done via computers, thanks to the foundational work of these three scientists who created powerful programs that are used to understand and predict chemical processes. These computer models have become crucial for chemical advances among today’s researchers.
Much of the Nobel Prize-winning research of Drs. Karplus, Levitt and Warshel is represented in the CAS databases, with more than 1,300 publications among them since the early 1970s and thousands of citations to their ground-breaking research. Examples of highly cited papers from their research are below:
- Karplus, Martin, et al. All-atom empirical potential for molecular modeling and dynamics studies of proteins. J. Phys. Chem. B., 1998, 102, 3586-3616. [see it in SciFinder]
- Levitt, Michael. Accurate modeling of protein conformation by automatic segment matching. J. Mol. Biol., 1992, 226(2), 507-33. [see it in SciFinder]
- Warshel, A.; Levitt, M. Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme. J. Biol. Chem. 1976, 103(2), 227-49. [see it in SciFinder]
- Warshel, A.; Karplus, M. Calculation of ground and excited state potential surfaces of conjugated molecules. I. formulation and parametrization. J. Am. Chem. Soc. 1972, 94(16), 5612-25. [see it in SciFinder]
CAS congratulates the 2013 Nobel Laureates in Chemistry for their important contributions to science!